Background: Herpes simplex viruses (HSV) are human pathogens that establish lytic and latent infections. Reactivation from latency occurs intermittently, which represents a life-long source for recurrent infection. The role of immune factors in the control of recurrent symptomatic HSV lesions is complex and the exact role of cytokines remains unclear. Objective: To assess the levels of tumor ne...

Herpes B-virus,cercopithecine herpesvirus 1;herpesvirus simian endemic in Asian macaques is related to herpes simplex(HSV) type 1 in humans; infection with herpes B-virus in humans can result in fatal encephalitis and neurologic impairment. Human infections have been by bites, scratches, and percutaneous inoculation. HerpesB-virus infection causes minimal morbidity in macaques. Inhumans herpes ...

Concurrent reactivation of herpes simplex and varicella zoster viruses is rare. Here, we describe the case of an elderly patient with herpes labialis and herpes zoster manifesting as a right-side facial eruption with vesicles and crusting. The loop-mediated isothermal amplification (LAMP) assay demonstrated the presence of both herpes simplex virus type 1 and varicella zoster virus in swab samp...

Type-specific vaccines containing heat-inactivated herpes simplex hominis virus type 1 or 2 have been developed for the treatment of herpes simplex genitalis. When patients with recurrent herpes genitalis were treated with the type 2 vaccine the clinical course of the disease improved and the eruption-free interval was extended. In severe cases, especially in permanent genital herpes, the concu...

FAMVIR, a prodrug of penciclovir, is a nucleoside analogue DNA polymerase inhibitor indicated for: Immunocompetent Adult Patients (1.1) • Herpes labialis (cold sores) • Genital herpes o Treatment of recurrent episodes o Suppressive therapy of recurrent episodes • Herpes zoster (shingles) HIV-Infected Adult Patients (1.2) • Treatment of recurrent episodes of orolabial or genital herpes Limitatio...