Background: Hepatitis B is an important infectious disease.  Since several years ago, mass vaccination against this viral infection has become as part of routine vaccination schedule of Iran.  However, some healthy neonates, children and adults fail to generate a protective antibody response after vaccination.Objectives: To investigate distribution of HLA class-I and class-II antigens in health...

BACKGROUND Transcatheter mitral valve repair (TMVR) has been shown to have acute effects on mitral valve geometry in patients with functional mitral regurgitation (FMR). This study investigates the impact of MitraClip® therapy-induced annular remodeling on clinical outcome and mitral regurgitation in heart failure patients. METHODS TMVR was performed successfully in 45 patients with FMR. In t...

background and aims: cytomegalovirus (cmv) has worldwide distribution, and its prevalence rate depends on factors such as economic and geographical conditions. an important way of the virus transmission is via blood. due to high prevalence of anti-cmv antibodies in blood donors and lack of data concerning its seroprevalence in the region, this study was carried out to determine the prevalence r...

The crosstolerance hypothesis suggests that animals sharing antigens with some microorganisms will produce low antibody levels in the early part and high levels in the latter part of an infection. Antibody responses have been measured in high responder B10.M and B10.D2 mice and low responder C3H and A.Thy-1.1, as well as F1 hybrids (B10.M X A.Thy-1.1) and (B10.M X C3H/He), after repeated immuni...

conclusions the prevalence of hbv infection among donors in duhok was comparable with those of reports from other parts of iraq. education and immunization should be initiated to target the high-risk groups. furthermore, a community-based study is recommended to study the prevalence of hbv and hcv infection in the population. background the prevalence of blood borne viral infection is escalatin...

The immune response (Ir) to the random copolymer GLphi depends upon the function of two Ir genes, Ir-GLphi-beta[beta] and Ir-GLphi-alpha[alpha], mapped to the I-A and I-E/C subregions of the major histocompatibility complex, respectively. In this paper, the site(s) of expression of the products of these two Ir genes was examined by evaluating T-lymphocyte proliferative responses of bone marrow ...

roglobulin, antimicrosome, or antiskeletal muscle autoantibodies whereas the generalised type showed a high titre and incidence of autoantibodies including AChR antibody.5 Seronegative patients or those with low AChR antibody may form a low responder subgroup of myasthenia gravis distinct from the high responders, who show a high titre of AChR antibody. Twelve patients (37 5%) were of the ocula...