background: management of lymphedema is a challenging issue in surgery.  a variety of operations have been used, albeit with little success. objective: to investigate the efficacy of testicular patch as a lymphatic conduit. methods: an incision was made on the inguinal area of 10 dogs and all lymph nodes of inguinal area were excised. the tunica albuginea and parenchyma near the hilum of testes...

The effects of regional hypotension on femoral resistance artery reactivity and morphology were investigated in spontaneously hypertensive rats (SHR) and control Wistar-Kyoto (WKY) rats. A partially constricting ligature (0.4 mm i.d.) was placed around the left external iliac artery at 5 weeks, which resulted in significantly reduced femoral mean arterial pressures distal to the ligature at 12 ...

The effects of regional hypotension on femoral resistance artery reactivity and morphology were investigated in spontaneously hypertensive rats (SHR) and control Wistar-Kyoto (WKY) rats. A partially constricting ligature (0.4 mm i.d.) was placed around the left external iliac artery at 5 weeks, which resulted in significantly reduced femoral mean arterial pressures distal to the ligature at 12 ...

PURPOSE CMC-544 is a CD22-targeted immunoconjugate of calicheamicin and exerts a potent cytotoxic effect against CD22+ B-cell lymphoma. This study evaluated antitumor efficacy of CMC-544 against systemically disseminated B-cell lymphoma. EXPERIMENTAL DESIGN Scid mice received i.v. injections of CD22+ Ramos B-cell lymphoma cells for their systemic dissemination. CMC-544, G5/44, CD33-targeted C...

Thyroid hormone (TH) receptor (TR) expression begins early in development in all vertebrates when circulating TH levels are absent or minimal, yet few developmental roles for unliganded TRs have been established. Unliganded TRs are expected to repress TH-response genes, increase tissue responsivity to TH, and regulate the timing of developmental events. Here we examined the role of unliganded T...

Rupture of the cranial cruciate ligament (CCL) in stifle is one most common causes hind-limb lameness middle-aged and old dogs. The treatment choice involves surgical extra- or intra-capsular stabilization knee joint, increasingly preferred tibial osteotomy techniques. Postoperative rehabilitation affected limb an equally important part treatment. paper describes three cases rupture dogs method...