objective: today, aids is considered as a global problem and many efforts to generate an effective vaccine against this disease have been made, but remain inconclusive. dna vaccines are a member of the new generation of vaccines that can efficiently stimulate the immune system. however, recent findings indicate low immunogenicity for these vaccines and it is believed that these types of vaccine...

objective: several vaccines against hiv have been investigated but none has been approved as an effective hiv vaccine. an approach that could induce stronger immune response against the pathogen is utilizing a multi-epitopic vaccine. this strategy was used in the design of several vaccines and resulted in improved immune responses. materials and methods: in this study a multi-epitopic fusion p...

objectives the aim of the present study was to estimate the prevalence of hiv infection in mashhad city. methods this cross sectional study was performed since may to september 2009 in mashhad, iran. a total of 1,678 individuals ranged 1-90 years of age were selected randomly from different geographical regions of the city, proportionate to sex and age distribution of the population according t...

although the hiv pandemic is witnessing a decline in the number of new infections in most regions of the world, the middle east and north africa (mena) has a rapidly growing hiv problem. while generating hiv data has been consistently increasing since 2005, mena’s contribution to the global hiv literature is just over 1% and the existing evidence often falls behind the academic standards. sever...