نتایج جستجو برای: hna
تعداد نتایج: 247 فیلتر نتایج به سال:
Epilepsy remains a devastating neurological disorder associated with recurrent, unprovoked, spontaneous epileptic seizures. Current treatments involve seizure suppression using antiepileptic drugs (AEDs); however, many patients remain refractory to current treatments or suffer serious side effects. In view of this continued need for more effective and safer AEDs, we have designed a novel compou...
The oligotrophic southeastern Mediterranean Sea (SEMS) is frequently exposed to desert-dust deposition which supplies nutrients, trace metals and a wide array of viable airbornemicroorganisms. In this study, we experimentally examined the impact of aerosol addition, collected during an intense dust storm event in early September 2015, on the biomass and activity of pico-phytoplankton and hetero...
The Boundary Element Method (BEM) is a powerful method for simulating scattering of acoustic waves which has many advantages, particularly when the problem concerns an object in an unbounded medium. Its applications are however limited in practice because standard schemes have a computational cost which grows extremely quickly as size and frequency is increased. Fundamentally this occurs becaus...
CONTEXT Despite recent progress in describing the common neural circuitry of emotion and stress processing, the bases of individual variation are less well understood. Genetic variants that underlie psychiatric disease have proven particularly difficult to elucidate. Functional genetic variation of neuropeptide Y (NPY) was recently identified as a source of individual differences in emotion. Lo...
Paroxysmal extreme pain disorder (PEPD), previously known as familial rectal pain (FRP, or OMIM 167400), is an inherited condition characterized by paroxysms of rectal, ocular, or submandibular pain with flushing. A genome-wide linkage search followed by mutational analysis of the candidate gene SCN9A, which encodes hNa(v)1.7, identified eight missense mutations in 11 families and 2 sporadic ca...
Sleep & Wakeup Technique Based Clustering Protocol-performance Evaluation in Wireless Sensor Network
In order to achieve data information, the Sensor Node’s should form into small groups as clusters in wireless sensor network. In Multi-hop sensor network, the Base-Station (sink) is might not be considered. That is why, the hot-spot problem may occur in this network. In this paper, we analyze the sleep & wakeup approach, in order to avoid the hot spot (WLAN) problem, which aims to increase the ...
BACKGROUND Septins are involved in a number of cellular processes including cytokinesis and organization of the cytoskeleton. Alterations in human septin-9 (SEPT9) levels have been linked to multiple cancers, whereas mutations in SEPT9 cause the episodic neuropathy, hereditary neuralgic amyotrophy (HNA). Despite its important function in human health, the in vivo role of SEPT9 is unknown. MET...
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