نتایج جستجو برای: hotspots

تعداد نتایج: 8181  

Journal: :Trends in Genetics 2020

2005
Stephan Groß Sabine Lein Sandra Steinbrecher

In jüngster Zeit nimmt die Verbreitung öffentlicher WLAN Hotspots immer mehr zu. Bisherige Systeme berücksichtigen jedoch den berechtigten Wunsch der Nutzer nach Schutz ihrer personenbezogenen Daten nur unzureichend. Wir stellen daher ein mehrseitig sicheres Abrechnungssystem vor, welches eine anonyme HotspotNutzung ohne aufwändige Authentifizierung ermöglicht. Hierdurch wird sowohl die Erstell...

2015
Henry M. Dewhurst Shilpa Choudhury Matthew P. Torres

Predicting the biological function potential of post-translational modifications (PTMs) is becoming increasingly important in light of the exponential increase in available PTM data from high-throughput proteomics. We developed structural analysis of PTM hotspots (SAPH-ire)--a quantitative PTM ranking method that integrates experimental PTM observations, sequence conservation, protein structure...

2015
Irene D. Alabia Sei-Ichi Saitoh Robinson Mugo Hiromichi Igarashi Yoichi Ishikawa Norihisa Usui Masafumi Kamachi Toshiyuki Awaji Masaki Seito Geir Ottersen

We identified the pelagic habitat hotspots of the neon flying squid (Ommastrephes bartramii) in the central North Pacific from May to July and characterized the spatial patterns of squid aggregations in relation to oceanographic features such as mesoscale oceanic eddies and the Transition Zone Chlorophyll-a Front (TZCF). The data used for the habitat model construction and analyses were squid f...

2008
Martin J. Hardcastle

I discuss the nature of ‘hotspots’ and ‘jet knots’ in the kpc-scale structures of powerful radio galaxies and their relationship to jet-environment interactions. I describe evidence for interaction between the jets of FRI sources and their local environments, and discuss its relationship to particle acceleration, but the main focus of the paper is the hotspots of FRIIs and on new observational ...

2012
Ananth Raghunathan Peter Chien Dan Boneh

The ability to identify location hotspots – locations that are currently popular – is frequently used by locationbased services to tune their recommendation and advertising systems. We present an efficient system that lets locationbased services identify location hotspots, but without learning who is at those locations. The service also learns popular activities at hotspots, but learns nothing ...

2017
Anne Vinkel Hansen Laust Hvas Mortensen Rudi Westendorp

Background: The study of regions with high prevalence of centenarians is motivated by a desire to find determinants of healthy ageing. While existing research has focused on selected candidate geographical regions, we explore the existence of hotspots in the whole the Denmark, which is a small and homogeneous country. Methods: We performed a Kulldorff spatial scan across the whole of Denmark, s...

2016
Teun Bousema Gillian Stresman Amrish Y. Baidjoe John Bradley Philip Knight William Stone Victor Osoti Euniah Makori Chrispin Owaga Wycliffe Odongo Pauline China Shehu Shagari Ogobara K. Doumbo Robert W. Sauerwein Simon Kariuki Chris Drakeley Jennifer Stevenson Jonathan Cox

BACKGROUND Malaria transmission is highly heterogeneous, generating malaria hotspots that can fuel malaria transmission across a wider area. Targeting hotspots may represent an efficacious strategy for reducing malaria transmission. We determined the impact of interventions targeted to serologically defined malaria hotspots on malaria transmission both inside hotspots and in surrounding communi...

2015
Xuan Zhu Scott Keeney

Running title: Transcription factors and meiotic double-strand breaks ABSTRACT Meiotic recombination initiates with DNA double-strand breaks (DSBs) made by Spo11. In Saccharomyces cerevisiae, many DSBs occur in " hotspots " coinciding with nucleosome-depleted gene promoters. Transcription factors (TFs) stimulate DSB formation in some hotspots, but TF roles are complex and variable between locat...

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