نتایج جستجو برای: hoxa11

تعداد نتایج: 175  

Journal: :Molecular medicine reports 2009
Vincenzo Martino Annalisa Bianchera Laura Reia Ovidio Bussolati Raffaella Fazzina Flora Marino Luca Montemurro Roberto Tonelli Andrea Pession Gian Carlo Gazzola Roberto Sala

The translocation t(9;11)(p22;q23) generates the MLL-AF9 oncogene and is commonly associated with monocytic acute myeloid leukemia (AML-M5; FAB-classification). For the oncogenicity of MLL-AF9, the (over)expression of several other genes, including selected HOXA cluster genes as well as MEIS1 (a HOX cofactor), is required. We previously showed that the down-regulation of MLL-AF9 expression is n...

2017
Ga Won Yim Hee Jung Kim Lee Kyung Kim Sang Wun Kim Sunghoon Kim Eun Ji Nam Young Tae Kim

PURPOSE The biological function of long non-coding RNAs (lncRNAs) is only partially understood; therefore, in this study, we investigated the expression of the novel HOXA11 antisense (HOXA11as) lncRNA and its oncogenic role in serous ovarian cancer (SOC). MATERIALS AND METHODS HOXA11as expression was examined in 129 SOC tissue samples by real time reverse transcription polymerase chain reacti...

2017
Xiao-Jie Sun Qiang Wang Baofeng Guo Xian-Ying Liu Bing Wang

The long non-coding RNAs (lncRNAs) regulating encoding transcripts/genes involved in Wnt signalling pathway in keloids is largely unclear. We used a pathway-focused lncRNA microarray to detect the differentiated expression profiles of both lncRNAs and genes involved in Wnt pathway, thus a total of 116 Wnt-targeted genes and 69 Wnt-related lncRNAs aberrantly expressed in keloids were initially i...

Journal: :genetics in the 3rd millennium 0
seyed mehdi kalantar vida mokhtari

homeobox (hox) genes are contributed in the genetic control of development of the body plan, pattern formation, and cell fate determination and the other several key developmental processes. hox genes are also known as selector genes because expression within a given section of the embryo will cause its cells to choose a particular developmental path. hox genes encode transcription factors that...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید