Introduction: One of the most common reasons of infertility is un-ovulatory period. Hormone therapy is the most common treatments of this type of infertility. Gonadotropins may exert toxic effects on the molecular organization of uterine surface, such as glycoconjugates. Glycoconjugates are the most important components of the uterine and trophoblast surface playing an important role in embryo ...

many findings point to the presence of a close relationship between the immune, endocrine and neurologic systems. for example the suppressive effects of β-human chorionic gonadotropin (β-hcg) on il-l production, the potentiative effect of enkephalins on lymphocyte functions and the suppressive effect of leuteinizing hormone (lh) on natural killer (nk) cell activities have been clearly establish...

The present study is designed to elucidate certain biological characteristics of urinary chorionic gonadotropin and to see what differences could be demonstrated between HCG in normal pregnancy and in the trophoblastic diseases. We have attempted the biological characterization of HCG using crude HCG and the purified HCG (12 ,000 I.U./mg) by zone electrophoresis on starch grain and chromatograp...

Introduction: The diagnosis of pregnancy from forensic bloodstains can be useful in cases infanticide, criminal abortions and missing person identification. Objective: This research illustrated the use a rapid, precise, tremendously responsive enzyme immunoassay kit designed for medical usage, which is put to good our lab qualitative HCG detection blood stains has proven tool Methods: concentra...

Kallmann's syndrome is a neuronal migration disorder characterised by anosmia/hyposmia and hypogonadotropic hypogonadism. We present a case of a 21-year-old man who was unable to sense smell since birth and who displayed non-development of secondary sexual characteristics for the past 10 years. Blood investigations showed low basal levels of serum follicle stimulating hormone (FSH), serum lutei...

We present the cases of two women with chronic ectopic pregnancies who presented with acute tubal rupture and hemoperitoneum despite negative beta-human chorionic gonadotropin (beta hCG) pregnancy tests. The appropriate screening use of beta hCG assays to ascertain pregnancy status, the mechanisms by which ectopic pregnancy may be seen with negative beta hCG tests, and the limitations of variou...

Treatment of human granulosa cells with human chorionic gonadotropin (hCG) or an analogue of its second messenger, cyclic AMP (cAMP), promotes a rapid accumulation of the messenger RNAs (mRNAs) for cytochrome P450 side-chain cleavage (scc) and adrenodoxin. A twofold increase in the cellular content of these mRNAs was observed within 4 h of exposure to 8-bromo-cAMP, and was maintained for up to ...

INDUCTION OF OVULATION IN THE HUMAN WITH HUMAN GONADOTROPINS.* By C. Lee Buxton and Walter Herrmann, Department of Obstetrics and Gynecology, Yale University School of Medicine. During the 33 years since human chorionic gonadotropin (hereafter to be designated as HCG) was shown to produce ovulation in small mammals, there have been numerous unsatisfactory attempts to stimulate human ovarian act...

Author for correspondence: Dr Gam Lay Harn School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Minden, Pulau Pinang, Malaysia. Tel: 604-6533888 ext 2208 Fax: 604-6570017 E-mail: [email protected] Abstract As a consequence of the abused of human chorionic gonadotropin αhCG) by male athletes, a reliable detection method for βhCG is highly desired in sport testing. hCG is misused by m...

Early determination of pregnancy viability is essential for women at risk for experiencing ectopic pregnancy or spontaneous abortion. Several markers of pregnancy viability have been identified including serial human chorionic gonadotropin (hCG) monitoring and sonography, in addition to several less commonly available biochemical markers. An ideal test would be readily available, inexpensive an...