Trichosanthin (TCS) is a type I ribosome-inactivating protein with potent inhibitory activity against human immunodeficiency virus type 1, and has been clinically applied in acquired immunodeficiency syndrome (AIDS) therapy. Previous studies revealed that TCS recognized human immunodeficiency virus type 1 (HIV-1) particles. Here, we investigated the physical relationship between TCS and HIV-1 p...

Trichosanthin (TCS) is a type I ribosome-inactivating protein with potent inhibitory activity against human immunodeficiency virus type 1, and has been clinically applied in acquired immunodeficiency syndrome (AIDS) therapy. Previous studies revealed that TCS recognized human immunodeficiency virus type 1 (HIV-1) particles. Here, we investigated the physical relationship between TCS and HIV-1 p...

Acquired Immune Deficiency Syndrome (AIDS) is a collection of symptoms that arise due to decreased immunity caused by HIV infection. Human Immunodeficiency Virus (HIV) type virus infects white blood cells which causes decrease in human immunity. Efforts are being made at this time for people with namely Antiretroviral treatment (ARV). This study aims analyze the factors influence utilization AR...

Changes in Testing for Human Immunodeficiency Virus, Sexually Transmitted Infections, andHepatitis C Virus in Opioid Treatment Programs Opioid dependence is a risk factor for human immunodeficiency virus (HIV), sexually transmitted infections (STIs), and hepatitis C virus (HCV) infection.1 Opioid treatment programs, which provide treatment to more than 300 000 opioid-dependent individuals in th...

Like human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV), HIV-2 requires a coreceptor in addition to CD4 for entry into cells. HIV and SIV coreceptor molecules belong to a family of seven-transmembrane-domain G-protein-coupled receptors. Here we show that primary HIV-2 isolates can use a broad range of coreceptor molecules, including CCR1, CCR2b, CCR3, CCR4, CCR5...

Long-acting (LA) cabotegravir/rilpivirine (CAB/RPV) is a complete regimen for the management of human immunodeficiency virus type 1 (HIV-1) infection to replace their oral antiretroviral therapy (ART) when they have been virologically suppressed. We present case successful achievement undetectable HIV RNA viral load levels in an acquired syndrome (AIDS) patient with long-standing virologic fail...

T HE HUMAN immunodeficiency virus (HIV) has been identified as the causal agent for the acquired immunodeficiency syndrome (AIDS). Infection with this virus has been associated with a broad range of clinical outcomes, particularly evident in the hematopoietic system. Impaired hematopoiesis, immune-mediated cytopenia, and altered coagulation parameters have been described following HIV infection...

A number of CD4+ T cell lines were compared for their ability to act as target cells for human immunodeficiency virus (HIV) infection in syncytium- and plaque-forming assays. MT-4 and C8166 cells were the most sensitive indicator cells for HIV- and simian immunodeficiency virus (SIV)-induced cytopathic effects, and gave rise to macroscopic (MT-4) and microscopic (C8166) plaques. The MT-4 plaque...

conclusions upon our results, tattooed people even with a small size of tattoo on the body are more at risk for hcv, hbv, and hiv infection. results among the 63 patients with tattoos (21% female, 79% male, age range:16 to 79-years-old), four patients (6.3%) tested positive for hbsag and pcr-hbv, seven patients (11%) tested positive for hcv, and five (7.9%) tested positive for hiv. the last gro...

background: our study aimed to determine if alteration of metabolic parameters is associated with the severity of human immunodeficiency virus (hiv) infection, progress to acquired immunodeficiency syndrome (aids), or with the type of antiretroviral treatment (art).materials and methods: in a cross-sectional study among 114 hiv infected patients, we measured hematological and biochemical parame...