Human interleukin-2 production in insect (Trichoplusia ni) larvae: effects and partial control of proteolysis. Title Human interleukin-2 production in insect (Trichoplusia ni) larvae: effects and partial control of proteolysis. Publication Type Journal Article Year of Publication 1999 Authors Pham, MQ, Naggie, S, Wier, M, Cha, HJ, Bentley, WE Journal Biotechnol Bioeng Volume 62 Issue 2 Paginati...

Interleukin-1 has been implicated as a mediator of recurrent pericarditis. The efficacy and safety rilonacept, an interleukin-1α interleukin-1β cytokine trap, were studied previously in phase 2 trial involving patients with

Interleukin-2 (IL-2) regulates different functions of various lymphoid cell subsets. These are mediated by its binding to the IL-2 receptor (IL-2R) composed of three subunits (IL2-Ralpha, -beta, and -gamma(c)). IL-2Rbeta is responsible for the activation of several signaling pathways. Ectodomain shedding of membrane receptors is thought to be an important mechanism for down-regulation of cell s...

BACKGROUND Human cytomegalovirus infection is the most frequent viral complication in patients undergoing hematopoietic stem cell transplantation. We investigated the development of human cytomegalovirus-specific T cells in adult recipients of hematopoietic stem cell transplants. DESIGN AND METHODS From May 2003 through October 2006 a total of 45 patients were monitored for human cytomegalovi...

AIM: to study the cytokine link of immunity in patients with new coronavirus infection COVID-19 and possibility using these data predict risk lung tissue damage.
 MATERIALS AND METHODS: Patients diagnosed were divided into 4 groups depending on severity disease: 1 asymptomatic patients; 2 damage amount 25%; 3 50%; 75% (according results computed tomography). Immunological studies performed...

We report here the cloning and characterization of four new members of the interleukin-1 (IL-1) family (FIL1delta, FIL1epsilon, FIL1zeta, and FIL1eta, with FIL1 standing for "Family of IL-1"). The novel genes demonstrate significant sequence similarity to IL-1alpha, IL-1beta, IL-1ra, and IL-18, and in addition maintain a conserved exon-intron arrangement that is shared with the previously known...