Most viruses in human skin are known to be human papillomaviruses (HPVs). Previous sequencing of skin samples has identified 273 different cutaneous HPV types, including 47 previously unknown types. In the present study, we wished to extend prior studies using deeper sequencing. This deeper sequencing without prior PCR of a pool of 142 whole genome amplified skin lesions identified 23 known HPV...

background: epidemiologic and molecular evidences have established a strong link between high risk types of human papilloma virus and a subgroup of head and neck squamous cell carcinomas (hnscc). we evaluated the frequency of hpv positivity in hnscc and its relationship to demographic and some risk factor variables in an open case- control study. methods: fourteen recently diagnosed patients wi...

human papillomaviruses (hpvs) infect mucosal and cutaneous epithelia and cause malignant and benign neoplastic lesions. human papillomaviruses cause 250000 deaths per year from cervical cancer most often in developing countries. this major public health problem make them important targets in the search for human papillomaviruses detection methods that may play a role in cervical cancer screenin...

Some human squamous cell carcinomas contain DNA of human papillomaviruses (HPV) and express RNA from the E6 and E7 genes. We have examined the effect of plasmids that express antisense RNA of these genes on the growth of the human cancer cell lines HeLa, C4-1, and 1483, which contain HPV type 18 DNA. As controls, the human cancer cell line 183 and the Vero line of monkey kidney cells were used,...

Aim: Head and Neck Squamous Cell Carcinoma (HNSCC) is a global health problem whose incidence varies by geographic region race according to risk factors. Human papillomavirus (HPV) infection significant factor for HNSCC. HPV-16 HPV-18 are two forms of HPV that carcinogenic. HNSCCs positive have better prognosis rather than negative. The purpose this research was characterize HPV-16, -18 variati...

  Background: Cervical cancer is the second most common cancer in the world among women and human papilloma virus (HPV) plays a major role in its development. The aim of this study was to determine the frequency of HPV type 16 and 18 in cervical discharge by polymerase chain reaction (PCR) method in women with atypical biopsy or papsmear. Method: This case- control study was performed on wome...

abstract background and aims: cervical cancer is among leading causes of cancer related death in women and human papilloma virus (hpv) is one of the important risk factor of this cancer. the aim of the present study was to develop a pcr method for identification of a high carcinogenic type of hpv, hpv 18 using e6 gene as a marker in patients with cervical cancer materials and methods: 92 formal...

the aim of this study was to ascertain the prevalence of human papillomavirus (hpv) 16/18 in oral squamous cell carcinoma (oscc) and normal oral mucosa in iranian individuals with oscc and their association with various risk factors. the investigation followed a hospital-based case-control design. cases were individuals with diagnosed oscc, age- and sex-matched with controls. sixty-six paraffin...