نتایج جستجو برای: human peripheral blood mononuclear cells

تعداد نتایج: 3166326  

2013
Anat Gafter-Gvili Boris Zingerman Benaya Rozen-Zvi Yaacov Ori Hefziba Green Ido Lubin Tsipora Malachi Uzi Gafter Michal Herman-Edelstein

BACKGROUND DNA repair is a cellular defence mechanism responding to DNA damage caused in large part by oxidative stress. There is a controversy with regard to the effect of red blood cells on DNA damage and cellular response. AIM To investigate the effect of red blood cells on H2O2-induced DNA damage and repair in human peripheral blood mononuclear cells. METHODS DNA breaks were induced in ...

Journal: :Haematologica 2012
Konstantia I Pavlaki Maria-Christina Kastrinaki Michail Klontzas Maria Velegraki Irene Mavroudi Helen A Papadaki

BACKGROUND Chronic idiopathic neutropenia is characterized by immune-mediated suppression of neutrophil production. Because patients with immune-mediated bone marrow failure syndromes display age-inappropriate telomere shortening in leukocytes, we investigated telomere lengths in peripheral blood mononuclear cells and granulocytes of patients with chronic idiopathic neutropenia. DESIGN AND ME...

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