introduction the umbilical cord anomalies directly effect on the life quality of the fetus. it can lead to fetal death or many problems during pregnancy and delivery. early detection of these abnormalities is of particular importance. case presentation we report a case of thin cord syndrome (tcs) in a 30-year-old pregnant woman with suprapubic pain. after termination of pregnancy, histopatholog...

BACKGROUND AND OBJECTIVES Severe anaemia, for which a blood transfusion can be life saving, is common in hospitalized children in sub-Saharan Africa but blood for transfusion is often in short supply. Umbilical cord blood is usually thrown away but could be a useful source of red cells for small volume transfusions in young children in this setting. The objective of this study was to evaluate t...

introduction hemoglobin (hb) levels in fetus increase with progression of pregnancy, reaching highest levels in life. hb serves as iron reserve in fetus and is needed for the infant to adapt with anemia. many factors can decrease hb levels at birth and lead to accelerated physiological anemia. hence, the infant would require earlier administration of iron drops. identification of these factors ...

Posthemorrhagic anemia is a rare but important cause of anemia in neonates, second only to hemolytic anemia of newborn. Most cases of posthemorrhagic anemia are reported from fetomaternal hemorrhage or umbilical cord accidents in utero. This case report describes a preterm infant who developed severe anemia and shock immediately after delivery related to an acute hemorrhage through patent umbil...

Aims: Umbilical cord blood (UCB) has been recently considered as an alternative source of hematopoitic progenitor cells for clinical application. The parameters commonly used to evaluate a UCB unit and predict transplant outcomes have been total nucleated cell count (TNCs), CD34+ cells concentration and total volume of cord blood collected. The volume of cord blood collection is also important ...

many investigators have used xenogeneic, especially murine stromal cells and fetal calf serum to maintain and expand human stem cells. the proliferation and expansion of human hematopoietic stem cells in ex vivo culture were examined with the goal of generating a suitable protocol for expanding hematopoietic stem cells for patient transplantation. using primary fetal liver cells, we established...

brain injuries that caused by strokes (result of intra partum ischemia) are a frequent cause of prenatal mortality and morbidity with limited therapeutic options. transplanting human mesenchymal stem cells (hmscs) indicates improvement in hypoxic ischemic brain injury (hibd) by secretion growth factor stimulating repair processes (hmscs) known as multi potent cells which isolated from bone marr...

ex vivo expansion of human umbilical cord blood cells (hucbc) is explored by several investigators to enhance the repopulating potential of hucbc. the proliferation and expansion of human hematopoietic stem cells (hsc) in ex vivo culture was examined with the goal of generating a suitable clinical protocol for expanding hsc for patient transplantation. using primary human mesenchymal stem cells...