The binding affinity between a probe hydrophobic particle and model hydrophobic plates with different charge (or dipole) densities in water was investigated through molecular dynamics simulation free-energy perturbation calculations. We observed a reduced binding affinity when the plates are charged, in agreement with previous findings. With increased charge density, the plates can change from ...

The interaction between energetically asymmetric hydrophilic and hydrophobic surfaces has fundamental and practical importance in both industrial and natural colloidal systems. The interaction forces between a hydrophilic silica sphere and a silanated, hydrophobic glass plate in N-methyl-2-pyrrolidone (NMP)-water binary mixtures were measured using atomic force microscopy (AFM). A strong and lo...

IL-2 signaling plays a central role in the initiation and activation of immune responses. Correspondingly, blockage of this pathway leads to inhibition of the immune system and would provide some therapeutic benefits. Basiliximab (Simulect), a therapeutic mAb drug with specificity against IL-2R alpha of T cells, was approved by U.S. Food and Drug Administration in 1998. It has been proven to be...

PURPOSE To measure the longitudinal chromatic aberration in vivo using psychophysical and wavefront-sensing methods in patients with bilateral implantation of monofocal intraocular lenses (IOLs) of similar aspheric design but different materials (hydrophobic Podeye and hydrophilic Poday). SETTING Instituto de Optica, Consejo Superior de Investigaciones Cientificas, Madrid, Spain. DESIGN Pro...

background and aims. adhesive permeability is hindered by application of an additional layer of hydrophobic resin, which increases its concentration within the hydrophilic layer, reduces its affinity to water, and enhances its physical properties. the aim of the present study was to evaluate the effect of a hydrophobic layer on the microleakage of class v composite restorations using different ...

INTRODUCTION Optimal pit and fissure sealing is determined by surface preparation techniques and choice of materials. The performance of pit and fissure sealant materials has been intensively investigated, yet no single product is reported as an ideal sealant. In children, moisture control during cavity preparation is always a big challenge, and hence, hydrophilic sealants have been developed. ...

Local differences in surface hydrophilicities/hydrophobicities of propyland arene-sulfonic-acid modified mesoporous silica and organosilica catalysts have been compared and correlated with their bulk catalytic properties for aqueous-sensitive organic reactions. Syntheses of propyland arene-SO3H-modified mesoporous silicas and organosilicas yield materials with different hydrophilicities, especi...