Na(+) absorption in the renal cortical collecting duct (CCD) is mediated by apical epithelial Na(+) channels (ENaCs). The CCD is subject to continuous variations in intraluminal flow rate that we speculate alters hydrostatic pressure, membrane stretch, and shear stress. Although ENaCs share limited sequence homology with putative mechanosensitive ion channels in Caenorhabditis elegans, controve...

Engineers can learn from nature for inspirations to create new designs. The internal structure of lotus roots with several oval holes was studied in this paper for engineering inspirations. The structural performance of lotus roots under outside water pressure was simulated and compared with various cross-sectional areas. The distribution of stresses in the cross-sectional area of lotus roots w...

The effects of hydrostatic extrusion on particle cracking and on the subsequent tensile properties of some prototypical particlereinforced metal–matrix composites are investigated. In most cases, tensile failure occurs through a plastic instability in accordance with the Considere criterion for necking. The corresponding failure strain is therefore dictated by the global flow and hardening char...

The present study was conducted to investigate current density of0.3 0.7 Al Ga N/ GaN multiple quantum well solar cell (MQWSC) under hydrostaticpressure. The effects of hydrostatic pressure were taken into account to measureparameters of 0.3 0.7 Al Ga N/ GaN MQWSC, such as interband transition energy, electronholewave functions, absorption coefficient, and dielectric con...

This paper presents a direct inversion approach for reconstructing the elastic shear modulus in soft tissue from dynamic measurements of the interior displacement field during time harmonic excitation. The tissue is assumed to obey the equations of nearly incompressible, linear, isotropic elasto-dynamics in harmonic motion. A finite element discretization of the governing equations is used as a...

Shock-induced spall in ductile metals is known to occur by the sequence of nucleation, growth and coalescence of voids, even in high purity monocrystals. However, the atomistic mechanisms involved are still not completely understood. The growth and collapse of nanoscale voids in tantalum are investigated under different stress states and strain rates by molecular dynamics (MD) simulations. Thre...

Previously, we have shown that pericardial constraint cannot be measured by true (hydrostatic) pressure except when an excess of pericardial fluid is present and that a device such as a balloon (which reflects radial contact stress as well as hydrostatic pressure) must be used. Since radial contact stress is the major component of the constraint exerted by the pericardium when little pericardia...