Due to the importance and various applications of nitriles especially in medicinal productions, a new method for conversion of aldehydes to nitriles has been presented. Several nitrile-containing aromatic compounds were synthesized through the treatment of various aldehydes and hydroxylamine hydrochloride as nucleophile in the presence of ferric hydrogen sulfate as a heterogeneous, efficient, a...

The reaction of diphenylcyclopropenone with several N-substituted hydroxylamine and primary amines are investigated. Most of these reactions led to ring opened or ring enlarged products, instead of the desired N-Oxide or imine. The reaction of cyclopropeneimine with peracid-another possible route to N-substituted cyclopropeneimine N-Oxide is studied. Most of the unexpected products are ide...

Aerobic ammonium oxidizing bacteria were first isolated more than 100 years ago and hydroxylamine is known to be an intermediate. The enzymatic steps involving conversion nitrite are still under discussion. For a long time it was assumed that directly converted by oxidoreductase. Recent evidences suggest the actual product of NO third, yet unknown, enzyme further converts nitrite. More recently...

ABSTRACT Hydroxylamine, NH2OH, is one of the already detected interstellar molecules with highest prebiotic potential. Yet, abundance this molecule found by astronomical observations rather low for a relatively simple molecule, ?10?10 relative to H2. This seemingly can be rationalized destruction routes operating on dust grains. In work, we tested viability hypothesis under several prisms, find...

The presence of cis-configured exchangeable ligands has long been considered a prerequisite for antitumor activity of platinum complexes, but over the past few years, several examples violating this structure-activity relationship have been recognized. We report here on studies with the geometric isomers of [PtCl2(acetoxime)2], cis-[dichlorobis(acetoxime)platinum(II)] [1 (cis)] and trans-[dichl...

Conflicting data have been collected so far on the action of nitric oxide (NO) on cholinergic interneurons of the striatum. In the present in vitro electrophysiological study, we reported that intracellularly recorded striatal cholinergic interneurons are excited by both hydroxylamine and S-nitroso-N-acetylpenicillamine, two NO donors. This excitation persisted unchanged in the presence of glut...

In order to characterize part of an active center of sodium and potassium ion transport adenosine triphosphatase, namely the active site of phosphorylation, the enzyme was phosphorylated with [32P]ATP and denatured with acid. The denatured [3SP]phosphoenzyme was digested to a limit [32P]phosphotripeptide with Pronase. The limit phosphotripeptide was compared with the synthetic model compounds, ...