نتایج جستجو برای: hydroxysteroid dehydrogenase

تعداد نتایج: 71506  

Journal: :The Biochemical journal 1999
T Lanisnik Rizner G Moeller H H Thole M Zakelj-Mavric J Adamski

17beta-Hydroxysteroid dehydrogenase (17beta-HSD) from the filamentous fungus Cochliobolus lunatus (17beta-HSDcl) catalyses the reduction of steroids and of several o- and p-quinones. After purification of the enzyme, its partial amino acid sequence was determined. A PCR fragment amplified with primers derived from peptide sequences was generated for screening the Coch. lunatus cDNA library. Thr...

Journal: :Journal of molecular endocrinology 2001
G Pelletier V Luu-The M El-Alfy S Li F Labrie

The subcellular distribution of steroidogenic enzymes has so far been studied mostly in classical endocrine glands and in the placenta. In the peripheral intracrine organs which synthesize sex steroids there is no indication about the organelles which contain the enzymes involved in steroid biosynthesis. We have thus investigated the subcellular localization of two enzymes involved in the produ...

2010
Guo-Xin Hu Bing-Hai Zhao Yan-Hui Chu Hong-Yu Zhou Benson T. Akingbemi Zhi-Qiang Zheng Ren-Shan Ge

The objective of the present study was to investigate the effects of genistein and equol on 3β-hydroxysteroid dehydrogenase (3β-HSD) and 17β-hydroxysteroid dehydrogenase 3 (17β-HSD3) in human and rat testis microsomes. These enzymes (3β-HSD and 17β-HSD3), along with two others (cytochrome P450 side-chain cleavage enzyme and cytochrome P450 17α-hydroxylase/17-20 lyase), catalyze the reactions th...

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