Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive age women.1 According to National Institutes of Health (NIH) criteria (presence of ovulatory dysfunction and hyperandrogenism, after exclusion of related disorders), PCOS is estimated to affect 6–8% of women in the US, the prevalence is estimated to be almost doubled to 15% when on the Rotterdam criteria are ...

OBJECTIVE Hyperandrogenemia is the most frequent endocrine disorder in fertile women causing a variety of negative metabolic disturbances. Establishing the diagnosis of androgen overproduction has important implications for the follow-up and treatment of patients. The aim of our study was to identify the optimal laboratory marker of androgen production by correlating the markers to the presence...

In May 2011, more than a decade after the International Association of Athletics Federations (IAAF) and the International Olympic Committee (IOC) abandoned sex testing, they devised new policies in response to the IAAF's treatment of Caster Semenya, the South African runner whose sex was challenged because of her spectacular win and powerful physique that fueled an international frenzy question...

CONTEXT The criteria for diagnosis of polycystic ovary syndrome (PCOS) have been modified and now include polycystic ovary morphology (PCOM). OBJECTIVE The purpose of this study was to determine the frequency of PCOS and PCOM in women with type 1 diabetes mellitus (DM1). DESIGN We evaluated the clinical, hormonal, and ultrasonographic characteristics in women with DM1 and compared them with...

Polycystic ovary syndrome (PCOS) affects 6–10% of women of reproductive age and is a common cause of infertility [1]. Its clinical manifestations can include menstrual irregularities, signs of androgen excess, and obesity [1]. Trials focusing on pregnancy as an outcome may place greater emphasis on anovulation as the identifying symptom, rather than the presence of polycystic ovaries or clinica...

BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of hyperandrogenism in women. Non-classic congenital adrenal hyperplasia (NCAH) is very close to PCOS. The diagnosis of hyperandrogenism is not based on the finding of decreased or increased levels of a single hormone. OBJECTIVE In our paper, we are going to test correlation between clinical signs and biochemical markers of ...

Consensus has recently been reached by international pediatric subspecialty societies that otherwise unexplained persistent hyperandrogenic anovulation using age- and stage-appropriate standards are appropriate diagnostic criteria for polycystic ovary syndrome (PCOS) in adolescents. The purpose of this review is to summarize these recommendations and discuss their basis and implications. Anovul...

Aim of this study was to evaluate the effect of vitamin D supplementation in obese, insulin resistant and vitamin D deficient PCOS women on biochemical and clinical hyperandrogenism and menstrual irregularity in comparison to effect of metformin or combined metformin plus vitamin D therapy. Thirty nine PCOS women were randomized into three groups and treated with alfacalcidiol (Group 1), combin...