Biological and synthetic materials often exhibit intrinsic variability in their elastic responses under large strains, owing to microstructural inhomogeneity or when elastic data are extracted from viscoelastic mechanical tests. For these materials, although hyperelastic models calibrated to mean data are useful, stochastic representations accounting also for data dispersion carry extra informa...

This study investigates the effects of different solid models on predictions of brain shift for three craniotomies. We created a generic 3D brain model based on healthy human brain and modeled the brain parenchyma as single continuum and constrained by a practically rigid skull. We have used elastic model, hyperelastic 1st, 2nd, and 3rd Ogden models, and hyperelastic Mooney-Rivlin with 2and 5-p...

This paper presents a study on stretch-induced wrinkling of thin polyethylene sheets when subjected to uniaxial stretch with two clamped ends. Three-dimensional digital image correlation was used to measure the wrinkling deformation. It was observed that the wrinkle amplitude increased as the nominal strain increased up to around 10%, but then decreased at larger strain levels. This behavior is...

There is a need to provide haptic and tactile feedback to surgeons during robot-assisted minimally invasive surgery (RMIS). Such feedback is also essential for palpation based diagnostic during cancer removal using MIS. There have been recent efforts at developing a mechatronic finger to mimic some of the palpation capabilities of a human finger. These mechatronic fingers typically record force...

Considering the nonlinear hyperelastic or viscoelastic nature of soft tissues has an important effect on modeling results. In medical applications, accounting nonlinearity begets an ill posed problem, due to absence of external force. Myocardium can be considered as a hyperelastic material, and variational approaches are proposed to estimate stiffness matrix, which take into account the linear ...

Accurate modeling of the high strain-rate response of healthy human knee cartilage is critical to investigating the mechanism(s) of knee osteoarthritis and other cartilage disorders. Osteoarthritis has been suggested to originate from regional shifts in joint loading during walking and other high strain-rate physical activities. Tibial plateau cartilage under compression rates analogous to walk...

We use the tight-binding potential and molecular mechanics simulations to study local and global instabilities in shear and simple shear deformations of three initially defectfree finite cubes of gold single crystal containing 3480, 7813, and 58,825 atoms. Displacements on all bounding surfaces are prescribed while studying simple shear deformations, but displacements on only two opposite surfa...

The research in the field of cardiovascular biomechanics is focused primarily on the heart and blood vessels, but the surrounding tissues, on the other hand, are often overlooked in the literature. This study shows that the human perivascular adipose tissue can significantly affect mechanical response of the human abdominal aorta. Analytical model of incompressible bilayer thick-walled closed c...

In accordance with the framework of hyperelastic isotropic material description it appears possible to replace work-conjugate stress and strain quantities by alternative pairs while other things left unaltered, i.e. based on a retained architecture energy density function. This replacement results in formally representing different kinds response behavior. may be recognized from various compara...