C D26, the T cell activation molecule, is a 110-kD gly-coprotein that is also present on epithelial cells of various tissues, including the liver, kidney, and intestine. CD26 possesses a known dipeptidyl peptidase (DPP)IV activity in its extracellular domain (1). A paper by Wesley et al. in this issue indicates a possible role for CD26/DPPIV in suppressing malignant transformation of melanocyte...

C D26, the T cell activation molecule, is a 110-kD gly-coprotein that is also present on epithelial cells of various tissues, including the liver, kidney, and intestine. CD26 possesses a known dipeptidyl peptidase (DPP)IV activity in its extracellular domain (1). A paper by Wesley et al. in this issue indicates a possible role for CD26/DPPIV in suppressing malignant transformation of melanocyte...

Drug-induced gingival hyperplasia is the increased growth of epithelium and submucosa which may cause bleeding loss teeth. Certain anticonvulsant, immunosuppressive, antihypertensive drugs are underlying in most cases. Among them, cases due to amlodipine very rare. Here, we discuss topic along with a case overgrowth induced by amlodipine. A 51-year-old female presented overgrowth. She was on be...

Background: Fibrous hyperplasia or epulis fissuratum is a name related to reactive tissue response chronic irritation and trauma caused by dentures that are not properly attached. Persistent the oral mucosa can cause carcinoma. The treatment management of becomes very challenging for geriatric patients.
 Objective: To discuss fibrous in patients with history hypertensive disease.
 Cas...

Sir, We read with interest the letter from Thestrup-Pedersen & Søndergaard (1) reporting the augmentation of len-tiges and naevi in a young male patient who had been self-injecting with " melanotan ". As in a case we initially reported (2), a clinically suspicious naevus was excised, with histology revealing a benign naevus, with no evidence of malignant transformation. The patient was also not...

T iny, membrane-bound packets of tinted protein, called melano-somes, dictate the color of human skin. Defi ciencies in melanosome production underlie pigmentation diseases, so it is important to understand how melanosomes are generated. But melanosomes are just one example of a larger family of lyso-some-related organelles, many of which are associated with pathologies when they are functional...

Objective: This study aimed to investigate the anti-inflammatory and analgesic mechanisms of a breast lump resolution detergent in rat model hyperplasia. Methods: A hyperplasia was established using injections estradiol benzoate combined with progesterone. The effects on nipple height diameter were observed, along its impact serum levels (E2), prolactin (PRL), progesterone (P). Additionally, ex...