BACKGROUND/AIMS Although gastric hyperplastic polyps are usually considered as benign lesions, a low risk of carcinomatous conversion is currently recognized. We aimed to identify the characteristics of hyperplastic polyps undergoing neoplastic transformation. METHODS A total of 269 gastric hyperplastic polyps from 216 patients removed by endoscopic polypectomy (EP) or surgical resection were...

Human tumor syndromes are usually caused by inherited or de novo mutations in tumor suppressor genes or oncogenes within the cells that give rise to the tumors [1,2]. In some occasions, the cells that give rise to tumors do not have intrinsic abnormalities in cell differentiation or proliferation but are forced into a hyperplastic state secondarily by neural or humoral factors. The latter pheno...

Hyperplastic gastric polyps are incidentally diagnosed during upper gastrointestinal endoscopy. They are known to cause gastric outlet obstruction and chronic blood loss leading to iron deficiency anemia. However, hyperplastic gastric polyp presenting as acute severe upper gastrointestinal bleeding is very rare. To the best of our knowledge, there have been two cases of hyperplastic gastric pol...

Recent studies have suggested that hyperplastic polyps may be benign precursor lesions for a distinct subset of colorectal tumors. We conducted a clinic-based case-control study to evaluate risk factors for hyperplastic polyps. Cases with hyperplastic polyps (n = 219), adenomas (n = 437), and both types of polyps (n = 138), along with colonoscopy-negative controls (n = 708), were identified at ...

BACKGROUND Serrated adenoma is a new morphological subtype of colorectal adenoma. The lesion provides a distinct morphological route to carcinoma, but the underlying genetic changes have not yet been investigated. AIMS To determine the frequency of K-ras mutation in serrated adenoma. METHODS The frequency of K-ras codon 12 point mutation in 20 serrated adenomas, five atypical hyperplastic p...

Objectives: The purpose of the study was to analyze the frequency and distribution of gingival lesions in MR Ambedkar Dental College, Bengaluru. Materials and methods: The material included the biopsies of all localized reactive hyperplastic lesions (LRHL) of the gingiva stored in the department’s database (1995-2011). The lesions were analyzed according to their location and the patient's age ...

Purpose: This retrospective study aimed to contribute to literature by investigating the types and distribution of intraoral localized reactive hyperplastic lesions (LRHLs) in Sivas. Patients and Methods: The histological diagnostic records of210 patientswhohad been treated for oral lesions from 1987 to 2008at the Department of Pathology at Cumhuriyet University were evaluated. The lesions were...

We report herein the case of a lobulated and pedunculated hyperplastic polyp in the third portion of the duodenum causing anemia and occult blood in stools, which was detected by capsule endoscopy (CE) and treated with snare polypectomy. A 71-year-old man was referred to our hospital because of anemia and occult blood in stools. Three months earlier, he had been admitted to another hospital bec...

BACKGROUND Kaposi sarcoma (KS) has features of both neoplastic growth and hyperplastic proliferation. It is the most common tumor seen in patients with HIV infection. Whether KS is a real tumor or a benign hyperplastic disease is not known. MATERIAL AND METHODS Tissues from KS and cutaneous hemangioma lesion DNA were extracted, and then digested with methylation-sensitive restriction endonucl...

This paper presents an unusual case of gingival ALCL, which mimicked a benign hyperplastic lesion that occurred in a 57-year-old white man representing the first clinical manifestation of acquired immunodeficiency syndrome (AIDS). The patient was referred to the Dental Clinic of PUCPR complaining of a lobulated nodule on the gingiva of his upper central incisors. The presence of advanced chroni...