نتایج جستجو برای: hypervitaminosis d
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The vitamin D(3) and nicotine (VDN) model is one of isolated systolic hypertension (ISH) in which arterial calcification raises arterial stiffness and vascular impedance. The effects of VDN treatment on arterial and cardiac hemodynamics have been investigated; however, a complete analysis of ventricular-arterial interaction is lacking. Wistar rats were treated with VDN (VDN group, n = 9), and a...
Vitamin D [1,25(OH)2D3] plays a crucial role in Ca2+ homeostasis by stimulating Ca2+ (re)absorption and bone turnover. The 1,25(OH)2D3 analog ZK191784 was recently developed to dissociate the therapeutic immunomodulatory activity from the hypercalcemic side effects of 1,25(OH)2D3 and contains a structurally modified side chain characterized by a 22,23-double bond, 24R-hydroxy group, 25-cyclopro...
ALTHOUGH calcification in the animal body is normaly confined to hypertrophic cartilage and osteoid, in certain abnormal or pathological conditions deposits of calcium salts may also be formed in other tissues, among which are the kidney, the lung and the arteries. Some of these conditions, for example hypervitaminosis D, are associated with exceptionally high concentrations of bloodcalcium or ...
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