Introduction: An impaired sense of smell has a remarkable impact on the quality of life. It is seen in a variety of neurodegenerative diseases such as Parkinson disease. In this study, we assessed the olfactory function in patients with Multiple Sclerosis (MS) by Sniff Magnitude Test (SMT).  Methods: A cross-sectional study was conducted on 48 patients with MS. A questionnaire, including demog...

M.AH, female, 54 years, born and raised in São Paulo, with repetition epistaxis, nasal obstruction and hyposmia for two years. A solid tumor was found in her nose, coming from the middle meatus and partially obstructing her left nasal cavity. We performed a contrasted CT scan of her paranasal sinuses and a nasofibroscopy with biopsy. The material was then sent for a pathology exam and immunohis...

Retired former workers of Matsuo Arsenic Mine of Miyazaki prefecture in Japan were subjected to extensive medical examination. The number of retired workers subjected to examination were 61 of 208 workers who were engaged in the works of the mine and were tracked down by the work rolls. These workers left the mine more than 15 years prior to the time of the examination. The main works in the mi...

An olfactory function test in 18 patients with Parkinson's disease (PD) and 10 age-matched control subjects was performed. Both detection and recognition thresholds were measured with five kinds of synthesized odorants (T & T olfactometry). Before each test, rhinoscopic inspections were performed to exclude subjects who could have respiratory hyposmia. Both detection and recognition thresholds ...

arkinson’s disease (PD) is a neurodegenerative disease relating to progressive degeneration of dopaminergic neurons in the substantianigra. The diagnostic criteria of PD were defined in a clinico-pathological study proposed by United Kingdom Parkinson’s Disease Society (UKPDS) in 1988. The consequence of degeneration of these neurons is depletion of dopamine in the central nervous system. There...

Kallmann's syndrome is a neuronal migration disorder characterised by anosmia/hyposmia and hypogonadotropic hypogonadism. We present a case of a 21-year-old man who was unable to sense smell since birth and who displayed non-development of secondary sexual characteristics for the past 10 years. Blood investigations showed low basal levels of serum follicle stimulating hormone (FSH), serum lutei...

We describe a practical technique of superior turbinectomy followed by posterior ethmoidectomy as a less invasive procedure for two-surgeon technique on endoscopic endonasal transsphenoidal surgery. After identification of the superior turbinate and the sphenoid ostium, the inferior third portion of the superior turbinate was coagulated and resected. This partial superior turbinectomy procedure...

Page 721 IgG4-related disease (RD) is a newly recognized systemic disease characterized by high serum IgG4 levels that affects multiple organs including salivary glands and the nasal and paranasal sinuses. Accordingly, many IgG4-RD patients complain about olfactory dysfunction. Yagi-Nakanishi et al have now investigated olfactory function in these patients. More than 50% of the patients suffere...