Cationic amphiphilic peptides are highly similar to native silaffins and silicateins for biosilicification in terms of their composition, amphiphilicity, and self-assembling propensity. To understand the relationship between organic molecular structures, molecular self-assembly and silica morphogenesis during biosilicification, we have prepared a series of short self-assembling peptide amphiphi...

Metastasis is the most lethal hallmark of esophageal squamous cell carcinoma (ESCC). The aim of the study is to identify key signaling pathways that control metastasis in ESCC. Highly invasive ESCC sublines (designated I3 cells) were established through three rounds of selection of cancer cells invading through matrigel-coated chambers. Gene expression profile of one of the I3 sublines was comp...

The reaction of bipyridine with hydroiodic acid in the presence of iodine gave two new polyiodide-containing salts best described as 4,4′-bipyridinium bis(triiodide), C10H10N2[I3]2, 1, and bis(4,4′-bipyridinium) diiodide bis(triiodide) tris(diiodine) solvate dihydrate, (C10H10N2)2I2[I3]2 · 3 I2 · 2H2O, 2. Both compounds have been structurally characterized by crystallographic and spectroscopic ...

The muscarinic M3 receptor (M3R) is a Gq-coupled receptor and is known to interact with many intracellular regulatory proteins. One of these molecules is Gβ5-RGS7, the permanently associated heterodimer of G protein β-subunit Gβ5 and RGS7, a regulator of G protein signaling. Gβ5-RGS7 can attenuate M3R-stimulated release of Ca(2+) from intracellular stores or enhance the influx of Ca(2+) across ...

Postoperative cognitive dysfunction (POCD) is a decline in cognitive performance after a surgery with anaesthesia. The exact reasons of surgery and/or anaesthesia resulting in POCD are unclear. The aim of this study is to investigate the effects of different concentration and duration time of isoflurane anaesthesia on cognitive performance and cellular mechanisms involved in learning and memory...

In bibliometrics, the association of “impact” with centraltendency statistics is mistaken. Impacts add up, and citation curves therefore should be integrated instead of averaged. For example, the journals MIS Quarterly and Journal of the American Society for Information Science and Technology differ by a factor of 2 in terms of their respective impact factors (IF), but the journal with the lowe...

The pressure-tuning Raman spectra of five solid, diiodine heterocyclic thioamide compounds (mbztS)I2 (mbztS = N-methyl2-mercaptobenzothiazole) (1); [(mbztS)2I] [I7] − (2); (pySH)I2 (pySH = 2-mercaptopyridine) (3); [(pySH)(pyS] [I3] − (4); (thpm)(I2)2 or possibly [(thpm)I2] [I3] − (thpm = 2-mercapto-3,4,5,6-tertahydropyrimidine (5) have been measured for pressures up to ∼ 50 kbar using a diamond...

The articles [18], [10], [11], [12], [22], [5], [14], [3], [6], [20], [7], [8], [9], [4], [19], [1], [2], [23], [24], [17], [16], [13], [21], and [15] provide the terminology and notation for this paper. For simplicity, we use the following convention: a, b are integer locations, f is a finite sequence location, i1, i2, i3 are instruction-locations of SCMFSA, T is an instruction type of SCMFSA,...

We present synchrotron-based I4d photoelectron spectroscopy experiments of solutions from LiI and LiI3 in water, ethanol, and acetonitrile. The experimentally determined solvent-induced binding energy shifts (SIBES) for the monatomic I(–) anion are compared to predictions from simple Born theory, PCM calculations, as well as multiconfigurational quantum chemical spectral calculations from geome...