Glaucoma is one of the leading causes of blindness worldwide. Historically, it has been considered an ocular disease primary caused by pathological intraocular pressure (IOP). Recently, researchers have emphasized intracranial pressure (ICP), as translaminar counter pressure against IOP may play a role in glaucoma development and progression. It remains controversial what is the best way to mea...

BACKGROUND Intracranial-pressure (ICP) monitoring is considered standard care for severe traumatic brain injury and is used frequently, but the efficacy of treatment based on monitoring in patients with hemorrhagic stroke has not been rigorously assessed. In this study, we investigated the clinical value of ICP monitoring in patients with hemorrhagic stroke. METHODS We conducted a randomized,...

OBJECTIVE Tympanic membrane displacement (TMD) measurements may be useful in the management of patients with hydrocephalus if they can be directly associated with measurements of ICP. We have compared TMD measurements using the Marchbanks Measurement System with invasive ICP monitoring. METHODS Twenty-nine patients who were undergoing routine invasive monitoring using a Camino fibre optic ICP...

Hydrocephalus is a condition characterised by enlarged cerebral ventricles, which in turn affects intracranial pressure (ICP); however, the mechanisms regulating ICP are not fully understood. A nonlinear signal processing approach was applied to ICP signals measured during infusion studies from patients with two forms of hydrocephalus, in a bid to compare the differences. This is the first stud...

objective: pseudotumor cerbri (ptc) is a clinical syndrome characterized by increased intra-cranial pressure (icp) without any evidence of a mass lesion or any obstructive process. the incidence is 0.9-2 per 100.000 people. it is more frequent in adults in the 20-30 years age group, especially obese women, and less common in pediatric age groups; 11-16 years old children may however suffer from...

OBJECT Deepening sedation is often needed in patients with intracranial hypertension. All widely used sedative and anesthetic agents (opioids, benzodiazepines, propofol, and barbiturates) decrease blood pressure and may therefore decrease cerebral perfusion pressure (CPP). Ketamine is a potent, safe, rapid-onset anesthetic agent that does not decrease blood pressure. However, ketamine's use in ...

BACKGROUND In an attempt to characterize the intracranial pressure-volume compensatory reserve capacity, the correlation coefficient (R) between the ICP wave amplitude (A) and the ICP (P) level (RAP) has been applied in the surveillance of neurosurgical patients. However, as the ICP level may become altered by electrostatic discharges, human factors, technical factors and technology issues rela...

BACKGROUND The invasive nature of the current methods for monitoring of intracranial pressure (ICP) has prevented their use in many clinical situations. Several attempts have been made to develop methods to monitor ICP non-invasively. The aim of this study is to assess the relationship between ultrasound-based non-invasive ICP (nICP) and invasive ICP measurement in neurocritical care patients. ...

INTRODUCTION Optic nerve sheath diameter (ONSD) measurement with bedside ultrasound has been shown in many studies to accurately detect high intracranial pressure (ICP). The accuracy of point-in-time ONSD measurement in the presence of ongoing fluctuation of ICP between high and normal is not known. Recent laboratory investigation suggests that reversal of optic nerve sheath distension may be i...

IMPORTANCE The present study is the largest on the use and effect of intracranial pressure (ICP) monitoring in pediatric trauma patients. OBJECTIVE To determine the effect of ICP monitoring on survival in pediatric patients with severe head injuries using the National Trauma Data Bank. DESIGN, SETTING, AND PARTICIPANTS The National Trauma Data Bank was queried (version 6.2, 2001-2006) for i...