Despite the pandemic status of COVID-19, there is limited information about host risk factors and treatment beyond supportive care. Immunoglobulin G (IgG) could be a potential target. Our aim was to determine incidence IgG deficiency associated in cohort 62 critically ill patients with COVID-19 admitted two German ICUs (72.6% male, median age: 61 yr). Thirteen (21.0%) displayed (IgG < 7 g/L)...

Objective To characterize T-cell receptors (TCRs) and identify target epitopes in multiple sclerosis (MS). Methods Peripheral blood mononuclear cells were obtained from 39 MS patients 19 healthy controls (HCs). TCR repertoires for α/β/δ/γ chains, diversity, V/J usage determined by next-generation sequencing. β chain compared with affectation status using a novel clustering method, Grouping of L...

In the framework of the littlest Higgs(LH) model, we consider the processes e+e− → νν̄H and e+e− → W ∗W ∗νν̄ → νν̄tt̄, and calculate the contributions of new particles to the cross sections of these processes in the future high energy e+e− collider(ILC) with √ S = 1TeV . We find that, with reasonable values of the free parameters, the deviations of the cross sections for the processes e+e− → νν̄H fr...

PURPOSE To investigate the relationship between immunoglobulin G (IgG)4-related disease (IgG4-RD) and thyroid eye disease (TED) with respect to IgG levels. PATIENTS AND METHODS A retrospective review of total IgG, IgG subclass, and thyroid stimulating immunoglobulin (TSI) levels in 24 patients with TED. RESULTS Five patients (20.8%) demonstrated serum IgG4 levels consistent with IgG4-RD wit...

The purpose of this study was to evaluate the role of both protein and radionuclide in the accumulation of 111In-labeled human immunoglobulin G (IgG) in infectious foci. In rats with a calf muscle infection, biodistribution was determined 2, 6, 24, and 48 hr after injection of a radiopharmaceutical. For IgG, human serum albumin (HSA) and human immunoglobulin A (IgA), all labeled with 111In, tar...

We report that Xenopus laevis oocytes can efficiently translate and insert heterologous membrane receptors into the oocyte plasma membrane, where they can be detected by the binding of either monoclonal antibodies or ligands. Thus, oocytes injected with mRNA from the mouse J774 macrophage-like cell line, the rat RBL-1 basophilic leukemia, and the U937 promonocyte cell line, bound 2.4G2 Fab, rat...

To investigate the IgG content and its variations in uterine fluid (UF) during the estrous cycle of the cow and to compare them with those of the blood serum (S), six pairs of serum and UF samples for each phase of the cycle selected out of 240 bovine genital tracts and blood samples were collected from Urmia abattoir. The UF samples were collected by gentle scraping of the endometrium using a ...

This study contributes to the environmental and socioeconomic sustainability literature by examining three important issues. First, examines effects of foreign direct investment (FDI) economic freedom on inclusive green growth (IGG) in sub-Saharan Africa (SSA). Second, we investigate whether interacts with FDI promote IGG. Third, identify minimum threshold required for cause foster The findings...