نتایج جستجو برای: il 31
تعداد نتایج: 283590 فیلتر نتایج به سال:
The novel cytokine IL-31 and its receptor have been shown to play a central role in bridging the immune system with neurons, epithelial surfaces connective tissues. Although increasing evidence has demonstrated their inflammation, involvement expansion of distinct leukocyte subsets is not fully understood. Detailed analyses Il31-transgenic (Eμ-Lck) mice indicated that next induction pruritus sk...
The aim of this study was to explore the diagnostic value of IL-31 levels in the pleural fluid and plasma to differentially diagnose tuberculous and malignant pleural effusion. We enrolled 91 cases, including tuberculous pleural effusion (TPE, n = 50), malignant pleural effusion (MPE, n = 41), other cases including pneumonia with pleural fluid, pulmonary tuberculosis and healthy people as contr...
pemphigus vulgaris is an autoimmune disease, in which the role of th17 cytokines needs to be further explored. this study was performed to assess serum levels of three interleukins (il) required for th17 differentiation (il-1β, il-6 and il-23) and two specific th17 cytokines (il-17 and il-22) in a group of patients with pemphigus vulgaris, at baseline, 3 weeks and 6 months after of treatment. c...
The novel cytokine IL-31 and its receptor have been shown to play a central role in bridging the immune system with neurons, epithelial surfaces connective tissues. Although increasing evidence has demonstrated their inflammation, involvement expansion of distinct leukocyte subsets is not fully understood. Detailed analyses Il31-transgenic (Eμ-Lck) mice indicated that next induction pruritus sk...
Background Pathogenesis of RA includes numerous interactions genetic and acquired defects in normal immunoregulation, one is disbalance pro- anti-inflammatory cytokines production. Basic treatment conception «treat-to-target», including biological agents Janus kinase (JAK) inhibitors. Tofacitinib the first JAK-inhibitors clinical practice, but data on its influence cytokine profile during cours...
background & objective: interleukin (il)-10 is an important anti-inflammatory and immunomodulatory cytokine. some authors believe that single nucleotide polymorphisms (snp) in the promoter region of the il-10 gene have been associated with susceptibility to hiv infection and progression to aids, but its role is not clearly defined yet. the present study was undertaken to evaluate the associ...
BACKGROUND Acute otitis media (OM) is a common disease which often develops through complex interactions between the host, the pathogen and environmental factors. We studied single nucleotide polymorphisms (SNPs) of genes involved in innate and adaptive immunity, and other host and environmental factors for their role in OM. METHODS Using Sequenom Massarray platform, 21 SNPs were studied in 6...
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