نتایج جستجو برای: imidazoline derivatives
تعداد نتایج: 105684 فیلتر نتایج به سال:
Acid-catalysed, '3+3' condensation of m-bispyrryl benzene derivatives with acetone afforded new non-aromatic macrocycles that can be converted to meso-alkylidenyl dibenzohexaphyrins carrying four exocyclic double bonds at meso-positions by DDQ oxidation.
Arginine contains the guanidinium group and thus has structural similarity to ligands of imidazoline and alpha-2 adrenoceptors (alpha-2 AR). Therefore, we investigated the possibility that exogenous arginine may act as a ligand for these receptors in human umbilical vein endothelial cells and activate intracellular nitric oxide (NO) synthesis. Idazoxan, a mixed antagonist of imidazoline and alp...
In the title compound, guanidinium chloridotrioxidochrom-ate(VI), (CH(6)N(3))[CrClO(3)], both the cation and anion are generated by crystallographic mirror symmetry, with one O and one N atom and the Cr, Cl and C atoms lying on the mirror plane. The bond lengths in the guanidinium cation are inter-mediate between normal C-N and C=N bond lengths, indicating significant delocalization in this spe...
It is known that moxonidine acts as an agonist at presynaptic 2-adrenoceptors of the postganglionic sympathetic nerve terminals and leads to a reduction in noradrenaline release. In addition, it is conceivable that I1-binding sites located in other regions of the preand postganglionic sympathetic neurons are involved in this effect. Our aim was to investigate whether and to what extent activati...
The impact of pre-corrosion on the performance an imidazoline-based corrosion inhibitor was evaluated with respect to inhibition uniform and localised in CO2-environments. Corrosion protection found be a function two factors, adsorption/film formation presence products. This effect most significant continuous FeCO3-rich layer high coverage steel surface, resulting only providing ?25 % overall a...
BACKGROUND Both alpha(2)-adrenergic and non--alpha(2)-adrenergic mechanisms seem to be involved in the hypotensive effect of imidazoline-like drugs. This study aimed at investigating how these 2 mechanisms work together to modify blood pressure (BP). METHODS AND RESULTS LNP 509, which appeared in this study to be devoid of alpha(2A)-adrenergic activity, was administered to anesthetized rabbit...
Background—Both 2-adrenergic and non– 2-adrenergic mechanisms seem to be involved in the hypotensive effect of imidazoline-like drugs. This study aimed at investigating how these 2 mechanisms work together to modify blood pressure (BP). Methods and Results—LNP 509, which appeared in this study to be devoid of 2A-adrenergic activity, was administered to anesthetized rabbits and wild-type (WT) mi...
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