Immature CD4(+)CD8(+) thymocytes rearrange their T cell receptor (TCR)-alpha gene locus to generate clonotypic alpha/beta TCR, after which a few cells expressing selectable TCR are signaled to further differentiate into mature T cells. Because of requirements for self-tolerance, immature CD4(+)CD8(+) thymocytes are programmed to die in the thymus in response to a variety of stimuli that do not ...

Cells infected with dengue virus release a high proportion of immature prM-containing virions. In accordance, substantial levels of prM antibodies are found in sera of infected humans. Furthermore, it has been recently described that the rates of prM antibody responses are significantly higher in patients with secondary infection compared to those with primary infection. This suggests that imma...

this study was conducted to determine the properties of islets of langerhans in pancreas of adult and immature, male and female maquee sheep. for this purpose, 20 samples of pancreas were used equally for each male and female, immature and adult animals. paraffin sections that they were stained by h&e; method were used for mean distribution and dimension of langerhans islets, and maldonado stai...

ovary and ovarian bursa of twelve female reproductive organ, six samples from each immature and mature buffaloes were collected from slaughterhouse. all samples were transferred to anatomy department of veterinary college, and they studied morphologically and morphometrically, length, wide, and thickness of ovaries, deep and wide of opening of ovarian bursa were measured. additionally, dimensio...

The human gastrointestinal tract is immature at birth, yet must adapt to dramatic changes such as oral nutrition and microbial colonization. The confluence of these factors can lead to severe inflammatory disease in premature infants; however, investigating complex environment-host interactions is difficult due to limited access to immature human tissue. Here, we demonstrate that the epithelium...

This paper concerns with a new delayed predator–prey model with stage structure on prey, in which the immature prey and the mature prey are preyed by predator and the delay is the length of the immature stage. Mathematical analysis of the model equations is given with regard to invariance of non-negativity, boundedness of solutions, permanence and global stability and nature of equilibria. Our ...

Although it is well established that immature B lymphocytes are exquisitely sensitive to tolerance induction compared with their mature counterparts, the molecular basis for this difference is unknown. We demonstrate that signaling by B cell antigen receptors leads to distinct and mutually exclusive biologic responses in mature and immature B cells: upregulation of CD86, CD69, and MHC class II ...

In infrapopulations of helminth parasites, density-dependent effects, through some form of intra- and interspecific competition, play an important role in shaping and regulating the infrapopulations. The mechanisms responsible for these processes have often been observed in laboratory studies and rarely studied under natural conditions. Here, 24 natural infrapopulations (77-447 individuals) of ...

The biology of the pentatomid Dichelops melacanthus (Dallas) feeding on cultivated and non-cultivated plants was studied in the laboratory. Nymph mortality varied from approximately 60 on corn (seed mature) to 77% on wheat (ear immature); no nymphs survived on seedlings of corn or wheat. Nymph developmental time on soybean, corn or wheat (seed, pod or ear) varied from 25.5 to 32.8 days. Body we...

Two models are proposed to simulate population growth of species with mature stage and immature stage in which there are parental cares for immature. It is assumed that the protection of mature to their immature reduces mortality of immature at the cost of reduction of reproduction. Dynamical adaptation of parental care is incorporated into the models, one of which is described with the proport...