Sixty-two patients were investigated for chronic intravascular hemolysis from 3 months to 6iS years following aortic valve replacement; 27 patients had Starr-Edwards prostheses and 35 fascia lata grafts. The findings are suggestive of a significantly higher incidence and degree of hemolysis in patients with Starr-Edwards prostheses compared to those with fascia lata grafts. In both groups regur...

The effect of osmotic protectors (sucrose and polyethylene glycols) and of a decrease in the detergent concentration at different points of hemolysis of human erythrocytes by sodium dodecyl sulphate on the shape of kinetic curves of hemolysis were studied. It is shown that slow detergent-induced hemolysis follows the colloid-osmotic mechanisms. Evidence is provided that rapid hemolysis by sodiu...

The last 2 decades have seen great progress in understanding the pathogenesis of cold agglutinin disease (CAD) and development effective therapies. Cold agglutinins can cause hemolytic anemia as well peripheral circulatory symptoms such acrocyanosis. We distinguish CAD, a well-defined clinicopathologic entity, from secondary syndrome. This review addresses histopathologic, immune phenotypic, mo...

Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in human. The aim of this study was to determine the prevalence of G6PD deficiency among children and evaluate its association with ABO/Rh blood groups. Method: Blood samples of 3401 asymptomatic children were analyzed and compared with 317 children who were admitted to hospital because of hemolys...

seizure is a rare presentation for acute hemolysis due to g6pd deficiency. we report a previously healthy boy who presented initially with seizure and cyanosis and subsequently acute hemolysis, due to glucose-6-phosphate dehydrogenase deficiency (g6pd) and probably secondary methemoglobinemia, following the ingestion of fava beans.

INTRODUCTION Paravalvular leak (PVL) related to a surgical prosthetic valve may be associated with clinically significant hemolysis. The influence of transcatheter PVL closure (TPVLC) on hemolysis remains uncertain. MATERIAL AND METHODS The prospective registry included patients undergoing TPVLC due to PVL-related heart failure and/or hemolysis. Procedural data, laboratory markers of hemolysi...

Evidence from microscopic studies indicates that hemolysis caused by the mumps virus hemolysin is a chemical type of hemolysis. Chromatographic analyses of the reaction mixture of erythrocytes and mumps virus following hemolysis indicate that hemolysis is not due to the action of a lecithinase A and that lysolecithin does not play a part in this process. The alteration of a component of the ery...

background one of the most important cause of severe neonatal hyperbilirubinemia is hemolysis including rh incompatibility.  the aim of this study was to assess the rate of hyperbilirubinemia due to hemolysis in rh positive neonates  born to rh negative mothers. methods in this retrospective study from march 1998 to february 2003, 60 icteric rh positive newborns that were born to rh negative mo...

The effect of hemolysis on the concentration of insulin in plasma was studied by a radioimmunoassay method. Plasma specimens with hemolysis have apparently lower insulin concentrations than plasma specimens without hemolysis, probably owing to the ability of red cell constituents to degrade insulin. The effects of hemolysis on the radioimmunoassay of insulin are quantitated, and the necessity o...