Deficiences imunitaire acquises Les , deficits nnmumtaires pathologiques af­ systeme des phagocytes, l'immunite a mechation_ cellulare :t la synthese des im­ Illfnoglobulmes so1t separement, soit con­Jom temen t. La manifestation .clinique de ces deficits est la ,frequence _des mfections bacterielles, vir­ales et mycotiques.  Le triteJent s deficits immunitaire a part la therap1e antnnfectieu...

The WHO European Region has been declared polio-free since 2002. By 2010, inactivated polio vaccine (IPV) was the only polio vaccine in use in the EU/EEA for the primary vaccination of children. A systematic review of the literature on polio seroprevalence studies, complemented by the analysis of available vaccine coverage data, has been carried out with the aim of assessing the level of protec...

Assessing the health and condition of animals in their natural environment can be problematic. Many physiological metrics, including immunity, are highly influenced by specific context and recent events to which researchers may be unaware. Thus, using a multifaceted physiological approach and a context-specific analysis encompassing multiple time scales can be highly informative. Ecoimmunologic...

PURPOSE The aim of this study is evaluation of periodontal status and definition of periodontal treatment needs in HIV infected patients. MATERIAL AND METHODS We examined 49 HIV-infected subjects (19-52 years of age) and 49 non-infected patients as the control group. Periodontal status and treatment needs were evaluated by using CPITN - Community Periodontal Index and Treatment Needs. Aquired...

Uremia results in a relatively immunocompromised status, and patients under chronic dialysis have an elevated risk of developing herpes zoster (HZ). We sought to investigate the relationship between vitamin D status and immunity to varicella-zoster virus (VZV). A multicenter prevalent hemodialysis cohort was assembled between 2012 and 2013. We assayed the biochemical parameters, 25-hydroxy- (25...

CONTEXT Vaccine development to prevent congenital cytomegalovirus (CMV) infection has been impeded by the uncertainty over whether maternal immunity protects the fetus. OBJECTIVE To determine whether the presence of maternal antibodies to CMV significantly reduces the risk of congenital CMV infection in future pregnancies. DESIGN, SETTING, AND PARTICIPANTS Cohort study of 3461 multiparous w...

OBJECTIVES Tetanus, which is a vaccine preventable disease, remains a significant health concern. The mortality is especially high in elderly and farming is a significant risk factor for the disease. This study evaluates the serological immunity of tetanus and the related factors, in a farmer population. METHODS This cross-sectional study was carried out in a village located in the western pa...

Antigenically evolving pathogens such as influenza viruses are difficult to control owing to their ability to evade host immunity by producing immune escape variants. Experimental studies have repeatedly demonstrated that viral immune escape variants emerge more often from immunized hosts than from naive hosts. This empirical relationship between host immune status and within-host immune escape...