Surprisingly, immunosuppressive treatment can enhance the efficacy of conventional HIV-1 antiretroviral treatment, and can be beneficial for HIV-1infected patients. This argues for a role of target cell availability in limiting the HIV-1 infection, and is in agreement with mathematical models suggesting that immunosuppression may limit the outgrowth of drugresistant escape mutants. Immunosuppre...

Uveitis is a common association of juvenile idiopathic arthritis (JIA) that has previously been characterized by poor visual prognosis with limited options for effective treatment. Since corticosteroid treatment is not a preferred long-term option for most patients with this condition, systemic immunosuppressive therapy is frequently employed. The medical options for the treatment of JIA-associ...