The influence of sagittal plane prosthetic alignment changes on loads applied to the ispilateral knee was investigated using 5 transtibial amputee subjects. The goal was to determine which prosthetic alignment results in the most energy efficient standing and also minimises stresses on knee structures during standing. The electromyogram, the external mechanical loading of the prosthetic leg and...

BACKGROUND After unilateral total knee arthroplasty, frontal plane loading patterns on the operated knee remain pathological in the long term, but it is unclear how they change in the early postoperative period. Additionally, researchers have suggested that the non-operated knee bears greater frontal plane loads postoperatively, but this effect is unclear. The objective of the present study was...

Sharing in silico experiments is essential for the advance of research in computational biology. Consequently, the COMBINE archive was designed as a digital container format. It eases the management of files related to a modelling result, fosters collaboration, and ultimately enables the exchange of reproducible simulation studies. However, manual handling of COMBINE archives is tedious and err...

The paper focuses on optimization of lightweight sandwich panels with prismatic cores subject to bending loads in the two principal in-plane directions. Comparisons are made with optimal designs of panels with corrugated cores: a limiting case. When optimized for loading transverse to the prism axis, prismatic panels outperform those with corrugated cores, especially at lower loads. In contrast...

We analyze the asymptotic properties of an Euclidean optimization problem on the plane. Specifically, we consider a network with 3 bins and n objects spatially uniformly distributed, each object being allocated to a bin at a cost depending on its position. Two allocations are considered: the allocation minimizing the bin loads and the allocation allocating each object to its less costly bin. We...