The NewProt portal is a platform that gives users access to a broad range of protein engineering tools and services. On an embedded website users can interactively work with these tools and perform their computations supported by integrated workflows. The portal provides a tight integration of standard tools for protein engineering and workflow development. The concept of the NewProt project is...

We used the software Optferm to model and optimize the bioprocess of escherichia coli fermentation, simulating the conditions of a fed-batch bioreactor. The results, obtained by employing different AI approaches, provided useful orientation for nutrient feed strategies for increased productivity. In conclusion, we believe in silico tools can perform a rapid and valid optimization of bioprocesse...

MOTIVATION In silico experiments necessitate the virtual organization of people, data, tools and machines. The scientific process also necessitates an awareness of the experience base, both of personal data as well as the wider context of work. The management of all these data and the co-ordination of resources to manage such virtual organizations and the data surrounding them needs significant...

background: dermatophagoides farinae and dermatophagoides pteronyssinus are house dust mites (hdm) that they cause severe asthma and allergic symptoms. tropomyosin protein plays an important role in mentioned immune and allergic reactions to hdms. here, tropomyosin protein from dermatophagoides spp. was comprehensively screened in silico for its allergenicity, antigenicity and similarity/conser...

Asam urat jika diproduksi secara berlebih oleh tubuh dapat mengakibatkan pembengkakan, rasa nyeri dan kaku dipersendian. Pembentukkan asam di dihambat dengan cara menginhibisi kerja enzim xantin oksidase. Penelitian ini bertujuan mengidentifikasi senyawa aktif sirih merah yang aktivitas oksidase melalui penambatan molekuler (in silico). Metode in silico dilakukan yaitu terarah (site directed do...

Background: Bioinformatic approaches for designing vaccines have become a promising alternative to conventional methods. We herein designed a multi-epitope-based vaccine against colorectal cancer (CRC). Methods: Used peptides in the CRC vaccines were retrieved from databases of PubMed, Web of Science, Google Scholar, and Clinical trials. The adjuvants of Mycobacterial heparin-binding hemagglut...