purpose : to investigate the application of mitomycin-c 0.02% (mmc) in the photorefractive keratectomy (prk) procedure in correcting regressed myopia methods : eighteen eyes of 11 patients with a spherical equivalent (se) of less than -5 diopters (d) who had undergone laser in situ keratomileusis (lasik) more than 2 years before were operated on. at the end of the prk procedure, mmc was applied...

background:breast cancer remains the most common and second lethal cancer in females. her-2/neu is one of the most important amplified oncogene in breast cancer. the amplification of her-2 is correlated with decreased survival, metastasis, and early recurrence.  the amplification of her-2/neu gene and synthesis of the protein are reported in 10%-34% of breast cancer cases associated with tumor ...

background the incidence rate of gastric cancer in western countries has shown a remarkable decline in the recent years while it is still the most common cancer among males in iran. the proto-oncogene myc, located at 8q24.1, regulates almost 15% of human genes and is activated in 20% of all tumors. the amplification of myc and overexpression of its protein product are observed in 15 - 30% of ga...

in this study, doxycycline hyclate release behavior from in situ forming drug delivery systems investigated. these systems based on poly()lactide-co-glycolide)(50:50 dissolved in n-methyl-2-pyrrolidone that were evaluated in different concentrations. these systems are useful for local treatment of periodontal diseases. uv spectroscopy is used to determine drug concentration in release medium. a...

In studying of the in situ gravitational concentration process part feature for placer, the technological ability to transform the in situ massif placer structure is evident. The two main processes involved in altering the massif in situ have been examined and outlined in detail. The in situ disintegration of massif material results in a new massif gravitational stratification structure. Regula...

Copper nanoparticle based clay composite has been synthesized by in situ reduction of a copper ammonium complex ion and characterized by different analytical instruments. The copper nanoparticles were both intercalated and adsorbed on the surface with diameters of <5nm (for intercalated) and 25-30nm (for adsorbed). The composite showed good stability for over 3 months in air. Excellent antimicr...

Composite nanofibers composed of polyacrylonitrile (PAN)-based carbon nanofibers and bioactive glass (BG) nanoparticles have been prepared by electrospinning and in situ sintering. Morphology observation showed that the BG nanoparticles of size 20-50 nm were uniformly distributed on the surface of composite nanofibers with 350 nm average diameter after carbonization. Biological mineralization i...

Composite material is a combination of two or more materials having compositional variations and depicting properties distinctively different from those of the individual materials of the composite. A composite mixture having more than one fiber is known as hybrid composite During the past decade, considerable research effort has been directed towards the development of in situ Metal Matrices h...