The aim of the present study was to investigate the antimicrobial activity and phytochemical screening of Carica papaya, Piper nigrum and Datura stramonium plant extracts. Ethanol and Methanol were used as the solvents for extraction. The antimicrobial activities of these plant extracts were tested against the drug resistant Gram-positive and Gram-negative bacterial strains. The bacteria used i...

Ocular examination was normal except for internal ophthalmoplegia of the left eye. The left pupil did not constrict when pilocarpine drops of either 0.125% or 1% were applied to the eye suggesting pharmacological origin of the condition and excluding an Adie’s pupil and a third nerve palsy respectively. A detailed medical history helped to the final diagnosis of pharmacological mydriasis by rev...

Chemical investigation of the 50% ethanol eluate fraction from a macroporous resin of flowers of Datura metel L. collected in the Jiangsu Province of China resulted in the isolation of two new withanolides, baimantuoluoline G (1) and baimantuoluoside H (2). Their structures were elucidated as (12β,6β,22R)-1,10-seco-6,12,27-trihydroxy-26-oxo-witha-3,5,24-trienolide-1-oic acid-ε-lactone (1) and (...

Abstract Datura stramonium is a poisonous plant species reported in almost every corner of India which belongs to the family Solanaceae with well-known history ethno medicinal applications. The present study has attempted phytochemical screening Himachal Pradesh based on altitude differences. In study, methanol extracts D. were analyzed by gas chromatography-mass spectrometry (GC–MS) identify i...