poorly water-soluble drugs often suffer from limited or irreproducible clinical response due to their low solubility and dissolution rate. in this study, organic solvent-free solid dispersions (osf-sds) containing telmisartan (tel) were prepared using polyvinylpyrrolidone k30 (pvp k30) and polyethylene glycol 6000 (peg 6000) as hydrophilic polymers, sodium hydroxide (naoh) as an alkalizer, and ...

Aim: Present study was conducted to examine the modulatory effect of different essential oils on rumen fermentation pattern in vitro using wheat straw based diet (concentrate: wheat straw 50:50). Materials and Methods: Four essential oils i.e. cinnamon, garlic, oregano and rosemary oils were tested at concentration of 0, 30, 300 and 600 mg/litre (ppm) of total culture fluid using in vitro gas p...

This study aimed to identify chemical composition of Thymus kotschyanus essential oil (TKEO) and to evaluate the effects of different doses of TKEO on in vitro gas production, fermentation parameters, acidosis and protozoal population using a completely randomized design with four replicates. Two diets (D1: 100% forage and D2: 30% forage+70% concentrate) were incubated with buffered rumen fluid...

The objectives of this study were to determine the molecular weight of condensed tannins (CT) extracted from mangosteen (Garcinia mangostana L) peel, its protein binding affinity and effects on fermentation parameters including total gas, methane (CH4) and volatile fatty acids (VFA) production. The average molecular weight (Mw) of the purified CT was 2,081 Da with a protein binding affinity of ...

the aim of this study was to evaluate the effects of chemical treatments including urea (5%), ammonia (3.5%), calcium hydroxide (4%), sodium hydroxide (5%), sulphuric acid (5%) and hydrogen peroxide (5%) on ph, dm solubility, lignin, silica, phenolic compounds, cellulose and hemicellulose stucture and ruminal degradability of rice straw. after processing, the treated straw was ensiled for 1 mon...

this study was conducted to investigate the effects of different doses of salvia mirzayanii essential oils on gas production parameters, fermentation characteristics using gas production and dual flow continuous culture system. trearments in the gas production experiment was adding 0, 400, 800, 1200, 1600, 2000, 2400 and 4800 mg/l of salvia mirzayanii essential oils to the media. in the second ...

the aim of this study was to investigate the effect of bacterial inoculation on the fermentation and aerobic stability of corn silage and on the dry matter degradability and milk composition when fed to sheep or cows. four male sheep were selected to measure dry matter degradability of uninoculated (ucs) and inoculated (ics) corn silage. milk composition was measured for 22 holstein cows, separ...

The use of pesticides in modern agriculture is unavoidable because they are required to control weeds. Pesticides are poisonous; hence, they are dangerous if misused. Understanding the fate of pesticides will be useful to use them safely. Therefore, contaminations of water and soil resources could be avoided. The fates of pesticides in soils are influenced by their sorption, decomposition and m...

Abstract Purpose The present experiment aimed to evaluate date palm leaves (DPL) treated without or with fibrolytic enzymes as a feed for ruminants. Methods employed an in vitro wireless gas production system the dietary inclusion of DPL sun-dried, ensiled 45 days. different forms replaced berseem hay (300 g/kg diet) at 0, 25, 50, 75 and 100% diet. Results Dried linearly decreased asymptotic to...