نتایج جستجو برای: inactive dynamics
تعداد نتایج: 468961 فیلتر نتایج به سال:
In this paper, an asymptotic stability proof for a class of methods inexact nonlinear model predictive control is presented. General Q-linearly convergent online optimization are considered and result derived the setting where limited number iterations optimizer carried out per sampling time. Under assumption Lipschitz continuity solution, we explicitly construct Lyapunov function combined syst...
the purpose of the present study was to compare some biochemical markers of cancer diseases risk between two groups of active and inactive postmenopausal women. for this purpose, 74 postmenopausal women were required to complete baecke questionnaire. they were divided into two groups: active (age: 55.89±4.38 years, height: 156.93±0.05 cm, weight: 63.18±6.50 kg, body fat percentage: 26.25±6.29, ...
background: we aimed to explore whether maternal asymptomatic hepatitis b (hb) infection effects on pre-term rupture of membranous (prom), stillbirth, preeclampsia, eclampsia, gestational hypertension, or antepartum hemorrhage. methods: we searched the pubmed, scopus, and isi web of science from 1990 to feb 2015. in addition, electronic literature searches supplemented by searching the gray lit...
Activating mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase are frequently found in many cancers. It has been suggested that changes in the equilibrium between its active and inactive conformations are linked to its oncogenic potential. Here, we quantify the effects of some of the most common single (L858R and T790M) and double (T790M-L858R) oncogenic mutations on the co...
AmpD is a cytoplasmic peptidoglycan (PG) amidase involved in bacterial cell-wall recycling and in induction of β-lactamase, a key enzyme of β-lactam antibiotic resistance. AmpD belongs to the amidase_2 family that includes zinc-dependent amidases and the peptidoglycan-recognition proteins (PGRPs), highly conserved pattern-recognition molecules of the immune system. Crystal structures of Citroba...
The COP9 (Constitutive photomorphogenesis 9) signalosome (CSN), a large multiprotein complex that resembles the 19S lid of the 26S proteasome, plays a central role in the regulation of the E3-cullin RING ubiquitin ligases (CRLs). The catalytic activity of the CSN complex, carried by subunit 5 (CSN5/Jab1), resides in the deneddylation of the CRLs that is the hydrolysis of the cullin-neural precu...
Stored-product insects often live in an environment of spatially separated food patches that vary considerably in size, quality, and persistence. The movement of individuals among patches of food influences the probability that stored products will become infested and pest populations will persist within storage facilities, thus affecting many aspects of pest management. We examined how a major...
In the developing nervous system, controlled neurite extension and branching are critical for the establishment of connections between neurons and their targets. Although much is known about the regulation of axonal development, many of the molecular events that regulate axonal extension remain unknown. ADP-ribosylation factor nucleotidebinding site opener (ARNO) and ADP-ribosylation factor (AR...
Cell polarization, in which intracellular substances are asymmetrically distributed, enables cells to carry out specialized functions. While cell polarity is often induced by intracellular or extracellular spatial cues, spontaneous polarization (the so-called symmetry breaking) may also occur in the absence of spatial cues. Many computational models have been used to investigate the mechanisms ...
Signal transduction proteins such as bacterial sensor histidine kinases, designed to transition between multiple conformations, are often ruled by unstable transient interactions making structural characterization of all functional states difficult. This study explored the inactive and signal-activated conformational states of the two catalytic domains of sensor histidine kinases, HisKA and HAT...
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