The Principles-and-Parameters approach (Chomsky 1981) postulates that UG consists of the set of universal principles that are satisfied by any language, and parameters that define the points and the range of possible human languages. Under this approach, the process of language acquisition is a process of fixing the values of such parameters, and thus the elucidation of genetically endowed para...

The compounding cream market has exploded across the country in the past few years. There are numerous pharmacies promoting these products, many different combinations of topical medications available, and the cost of these formulations is quite high. This can be quite intimidating to a physician, especially when there is inadequate time available for them to thoroughly evaluate these products ...

FDA draft guidance on 503B compounding widely faulted.

Atherosclerotic plaque rupture can initiate stroke or myocardial infarction. Lipid-rich plaques with thin fibrous caps have a higher risk to rupture than fibrotic plaques. Elastic moduli differ for lipid-rich and fibrous tissue and can be reconstructed using tissue displacements estimated from intravascular ultrasound radiofrequency (RF) data acquisitions. This study investigated if modulus rec...

PURPOSE The estimated microbial contamination rate for complex, multiple-step, medium-risk-level compounding was studied. METHODS The results of evaluations of the aseptic technique of pharmacists and technicians in compounding complex USP medium-risk-level sterile preparations were compiled to estimate the microbial contamination rate. The testing took place in 2002 and 2003 at a single inst...

BACKGROUND The accuracy, safety and feasibility of, the compounding robot APOTECAchemo were evaluated in the clinical practice of Japan. METHODS Accuracy and precision of robotic preparations by APOTECAchemo was evaluated in 20 preparations of fluorouracil (FU) and cyclophosphamide (CPA) infusions by four pharmacists. Environmental and product contaminations with FU and CPA were evaluated by ...

A benchmark contamination rate for prefilled syringe compounding was determined by using a medium-fill-simulation method. One thousand thirty-five 1-mL tuberculin syringes were aseptically filled with 0.9 mL of sterile soybean-casein digest medium and capped. These syringes were placed into clear nonsterile plastic bags and incubated at 35 degrees C for seven days, then inspected for cloudiness...

Temporal compounding can be used to suppress acoustic noise in transthoracic cardiac ultrasound by spatially averaging partially decorrelated images acquired over consecutive cardiac cycles. However, the reliable spatial and temporal alignment of the corresponding frames in consecutive cardiac cycles is vital for effective implementation of temporal compounding. This study introduces a novel, e...

OBJECTIVES To design, implement, and assess the effectiveness of using a live video teleconferencing system to connect the main campus and a satellite campus during laboratory compounding exercises in a doctor of pharmacy (PharmD) program. DESIGN A new laboratory facility with identical equipment and supplies to the main campus was built at the satellite campus and teleconferencing equipment ...

Webster's dictionary defines cancer as a "pernicious, spreading evil...", a definition that is hard to debate. Cancer is a life-changing disease for both the patient with cancer and the family members. Compounding pharmacists have the resources to assist patients in reducing their pain, nausea, and other symptoms of cancer and the side effects of their cancer treatments. By providing a glossary...