We reviewed the clinical and morphological findings in 43 cases of monoclonal gammopathy of undetermined significance (MGUS). 9 of smoldering multiple myeloma (5MM). and 23 of overt multiple myeloma (MM). In all cases. the patients physicians had requested a bone marrow examination because of the possibility of MM. In all 75 cases. 3H-thymidine labeling indices were performed. The plasma cell l...

We reviewed the clinical and morphological findings in 43 cases of monoclonal gammopathy of undetermined significance (MGUS). 9 of smoldering multiple myeloma (5MM). and 23 of overt multiple myeloma (MM). In all cases. the patients physicians had requested a bone marrow examination because of the possibility of MM. In all 75 cases. 3H-thymidine labeling indices were performed. The plasma cell l...

BACKGROUND In the breast cancer, the decision whether to administer adjuvant therapy is increasingly influenced by the Ki-67 proliferation index. In the present retrospective study, we investigated if this index could predict the therapeutic response to radiation therapy in small cell lung cancer (SCLC). METHODS Data from 19 SCLC patients who received thoracic radiation therapy were included....

RATIONALE Policy recommendations on contact investigation of HIV-seropositive patients with tuberculosis have changed several times. Current epidemiologic evidence informing these recommendations is considered low quality, and few large studies investigating the infectiousness of HIV-seropositive and -seronegative index cases have been performed in sub-Saharan Africa. OBJECTIVES We assessed t...

BACKGROUND We studied the transmission of rotavirus infection in households in peri-urban Ecuador in the vaccination era. METHODS Stool samples were collected from household contacts of child rotavirus cases, diarrhea controls and healthy controls following presentation of the index child to health facilities. Rotavirus infection status of contacts was determined by RT-qPCR. We examined facto...

PURPOSE In this study, the pulmonary arterial computed tomography obstruction index ratio, which indicates the degree and extent of thrombotic arterial occlusion, was calculated in cases with pulmonary thromboembolism. Our objectives were to investigate the value of this index for the identification of cases with massive pulmonary thromboembolism and to search for correlations between this inde...

background recent studies suggest an association between h. pylori infection and disorders such as iron deficiency anemia and growth delay. considering the high prevalence of h. pylori infection and iron deficiency anemia, this study was performed in order to evaluate their relevance in children undergoing an upper endoscopy. materials and methods in this case-control study, children aged 2 to ...

Background/Objective: It has been proposed that a narrow intercondylar notch may increase the risk of anterior cruciate ligament (ACL) injury but the data are conflicting. We performed this cross-sectional study to investigate if a narrow intercondylar notch width is a risk factor for ACL tears. Patients and Methods: All adult patients with knee problems, who were referred to the MRI department...