Characteristics and functional efficacy of digestive proteases of Catla catla, catla, Labeo rohita, rohu and Hypophthalmichthys molitrix, silver carp were studied. Total protease activity was significantly (P < 0.05) higher in rohu (1.219 ± 0.059 U mg protein min) followed by silver carp (1.084 ± 0.061 U mg protein min), and catla (0.193 ± 0.006 U mg protein min). Trypsin activity of silver car...

The common carp (Cyprinus carpio) belongs to the family Cyprinidae. In nature, carp live in the middle or lower reaches of a river with slow currents, or in marshes. Their habitats are usually weedy areas with a muddy bottom. Carp fry feed on zooplankton such as rotifers and copepods, but as they grow up they become benthic feeders, feeding on animals and other organic material. The cyprinids h...

In the capacitated arc routing problem (CARP) there is a network of streets, and on a subset of streets we have to make services (e.g. winter gritting, litter collection, school bus scheduling). A fleet of identical vehicles of limited capacity provides services; the fleet is based at a depot and each trip starts and ends at the depot. Each street can be traversed any number of times, with a kn...

A high-resolution genetic linkage map is essential for a wide range of genetics and genomics studies such as comparative genomics analysis and QTL fine mapping. Crucian carp (Carassius auratus) is widely distributed in Eurasia, and is an important aquaculture fish worldwide. In this study, a high-density genetic linkage map was constructed for crucian carp using 2b-RAD technology. The consensus...

Recent work shows that the block-parallel CARP-CG algorithm [Parallel Computing 36, 2010] is extremely effective on sparse nonsymmetric linear systems with very small diagonal elements, including cases with discontinuous coefficients. In contrast to most known solvers, the effectiveness of CARP-CG often improves as the diagonal elements become smaller. This property is shown to follow from the ...

OBJECTIVES The purpose of this study was to explore a novel disease gene for hypertrophic cardiomyopathy (HCM) and to evaluate functional alterations caused by mutations. BACKGROUND Mutations in genes encoding myofilaments or Z-disc proteins of the cardiac sarcomere cause HCM, but the disease-causing mutations can be found in one-half of the patients, indicating that novel HCM-susceptibility ...

A field isolate of pike fry rhabdovirus (PFR-80560) isolated from roach was tested for pathogenicity in fry of roach Rutilus rutilus L., common carp Cyprinus carpio L., grass carp Ctenopharyngodon idella Valenciennes and rainbow trout Oncorhynchus mykiss Richardson. The fish were experimentally exposed to the virus by immersion in a virus-seeded water-bath. We also compared the pathogenicity of...

Stearoyl-CoA desaturases (SCDs) are key enzymes of fatty acid biosynthesis whose regulation underpins responses to dietary, thermal, and hormonal treatment. Although two isoforms are known to exist in the common carp and human and four in mouse, there is no coherent view on how this gene family evolved to generate functionally diverse members. Here we identify numerous new SCD homologs in teleo...

MicroRNAs (miRNAs) are small non-coding RNA molecules that are processed from large 'hairpin' precursors and function as post-transcriptional regulators of target genes. Although many individual miRNAs have recently been extensively studied, there has been very little research on miRNA transcriptomes in teleost fishes. By using high throughput sequencing technology, we have identified 167 and 1...

INTRODUCTION The presence of a new autoantibody system, anti-carbamylated protein (anti-CarP) antibodies, has been identified in rheumatoid arthritis (RA). The presence of anti-CarP antibodies was evaluated in samples taken from individuals who subsequently developed RA before and after onset of symptoms and related to previously analysed antibodies against citrullinated peptides (ACPA specific...