The role of alcohol as the precipitating factor in the induction of acute attacks of acute intermittent porphyria was studied in an Indian population. Thirty-four teetotal patients with acute intermittent porphyria, in remission, were given 60 ml of 30% ethanol. Except for two patients, all had negative Watson-Schwartz tests prior to the alcohol. Within 24 hours, the Watson-Schwartz test became...

how to cite this article: shetty g, avabratha k.s, rai b.s. ring-enhancing lesions in the brain: a diagnostic dilemma. iran j child neurol. 2014 summer;8(3): 61-64. abstract the most common radiological abnormality seen in young indian patients with epilepsy is single small enhancing (ring/disc) computed tomographic (ct) lesions. the two most common differential diagnosis of this lesion in clin...

BACKGROUND Extra-hepatic portal vein obstruction due to portal vein thrombosis (PVT) is an important cause of portal hypertension in several regions including India. The cause of thrombosis in these patients remains unclear. We studied the frequency of mutations in genes for coagulation factors V and II (prothrombin) in 61 Indian patients with PVT and 49 healthy control subjects. METHODS The ...

INDIAN PEDIATRICS 19 VOLUME 53__JANUARY 15, 2016 he incidence of classical galactosemia in different countries has been reported to vary from 1 in 30,000 to 1 in 75,000 [1]. The exact population incidence in India is not known as mutations and importance of GALT gene analysis in the diagnosis of galactosemia in Indian patients. The same study also revealed that the mutational profile amongst In...

Perkash, A., Nair, A., Bhorchi, R., and Walia, B. N. S. (1971). Archives of Disease in Childhood, 46, 45. Haemolytic anaemia in Indian childhood cirrhosis. Fifty-five patients with Indian childhood cirrhosis were investigated for the occurrence of haemolysis and for its possible underlying mechanisms. Increased haemolysis was present in 76°/o of patients, and was severe in 12%. The degree of an...

Study of immunoglobulin levels in 16 Indian control subjects showed that, compared with a Danish control series, they had a significantly higher mean level of IgG, but not of IgA or IgM. By contrast, the IgG levels in eight patients with tropical sprue were decreased or low normal in six cases and raised in only one case. Two patients with tropical sprue had agamma-A-globulinaemia.Turnover stud...

Nasopharyngeal carcinoma (NPC) is rare among people of Indian ethnicity. A short retrospective case review of clinical records of Indian patients diagnosed with nasopharyngeal carcinoma in a period of 5 years was conducted. Their slides were further subjected to EBV encoded RNA (EBER) - In- situ Hybridization (ISH). The histologic subtype was nonkeratinizing carcinoma in all 4 patients. All wer...

this is a field study to determine the learning needs of hospitalized myocardial infarction (m!) patients, about activity, exercise, diet, medications, follow-up and recurrence predisposing factors, and their relation with demographic data in these patients, when they were discharged from cardiac unit. the study population comprised 92 randomly selected mi patients (77 men,26 women) on discharg...

BACKGROUND Crohn's disease is being increasingly diagnosed in the Indian subcontinent. Three apparently common mutations in the NOD2 gene are found in up to 30% of sporadic patients with Crohn's disease in western countries. We examined whether such mutations are also found in Indian patients with Crohn's disease. METHODS Venous blood was collected from 82 patients (age range: 7-65 years, 53 ...

There are few head-to-head comparisons of the commercial gamma interferon release assays (GIRAs). We compared the performance of the T-SPOT.TB and QuantiFERON-TB Gold In-Tube (QFT-IT) assays in patients with culture-proven pulmonary tuberculosis. Blood was drawn for both assays within 14 days of starting antituberculosis treatment. The QFT-IT indeterminate rate was 3.5%; the T-SPOT.TB failure r...