Instruction sequences with direct and indirect jump instructions are as expressive as instruction sequences with direct jump instructions only. We show that, in the case where the number of instructions is not bounded, there exist instruction sequences of the former kind from which elimination of indirect jump instructions is possible without a super-linear increase of their maximal internal de...

We present a dynamical technique for sampling the canonical measure in molecular dynamics. The method controls temperature by use of a device similar to that of Nosé dynamics, but adds random noise to improve ergodicity. In contrast to Langevin dynamics, where noise is added directly to each physical degree of freedom, our method relies on an indirect coupling to a single Brownian particle. For...

-The phonon-assisted band-to-band tunneling rate in crystalline silicon is calculated using the equilibrium Green's function formalism. Electron-phonon collisions, that balance the momentum, are included in the perturbation operator. Houston-type solutions are used for the time dependence of the Bloch states. RPA deeoupling yields a tractable expression for the differential tunneling conductivi...

Learning causal networks from large-scale genomic data remains challenging in absence of time series or controlled perturbation experiments. We report an information- theoretic method which learns a large class of causal or non-causal graphical models from purely observational data, while including the effects of unobserved latent variables, commonly found in many genomic datasets. Starting fro...

Nest construction is an impressive achievement for social insects. They employ templates (or patterns) in the environment to guide construction tasks and robot swarms can use similar mechanisms. Early work examined how a spatio-temporal varying template can be utilized by a swarm of minimalist robots to build the framework for a linear wall. From this, it became clear that a method for regulati...

The infrastructure sectors of developed countries have direct and indirect interdependencies. These interdependencies make national infrastructures extremely prone to the cascading effects of perturbations or failures. A negative event that reduces the operability of one infrastructure sector rapidly spreads to other sectors and back to the original sector in a feedback loop, amplifying the neg...

This paper presents a novel sliding mode control algorithm for an nth order nonlinear system suffering from parameters uncertainty and subjected to external perturbation. Using the proposed approach, the system will be on the sliding surface at the initial time (t=0). The idea is to eliminate the reaching phase and hence, a considerable amelioration of system robustness can be achieved. Moreove...

It is observed that low-lying transitions of an interstitial hydrogen adatom on a metallic lattice correspond classically to dipoles oscillating at frequencies where band electrons typically have a low electromagnetic absorption. Such transitions hence give rise to an essentially unscreened time-dependent perturbation of the lattice potential experienced by neighbouring hydrogen states. It is s...

While much attention has been focused on the force-generating mechanisms responsible for shaping developing embryos, less is known about the ways in which cells in animal tissues respond to mechanical stimuli. Forces will arise within a tissue as the result of processes such as local cell death, growth and division, but they can also be an indirect consequence of morphogenetic movements in neig...

The p53 pathway is inactivated in the majority of human cancers. Although this perturbation frequently occurs through the mutation or deletion of p53 itself, there are other mechanisms that can attenuate the pathway and contribute to tumorigenesis. For example, overexpression of important p53 negative regulators, such as murine double minute 2 (MDM2) or murine double minute 4 (MDM4), epigenetic...