نتایج جستجو برای: indoxyl sulfate

تعداد نتایج: 58952  

Journal: :Fibers 2021

A nanofiber mesh was prepared for the adsorption of indoxyl sulfate (IS), a toxin associated with chronic kidney disease. Removing IS is highly demanded efficient blood purification. The objective this study to develop zeolite composite remove efficiently. Eight zeolites different properties were used adsorption, where pore size 7 Å, H+ cations, and silica aluminum ratio 240 mol/mol exhibited h...

Journal: :Biomolecules 2023

Diabetic kidney disease (DKD) is one of the most debilitating complications type 2 diabetes mellitus (T2DM), as it progresses silently to end-stage renal (ESRD). The discovery novel biomarkers early DKD becomes acute, its incidence reaching catastrophic proportions. Our study aimed quantify previously identified metabolites from serum and urine through untargeted ultra-high-performance liquid c...

Journal: : 2023

Despite successful suppression of viral replication by antiretroviral drugs there is no significant increase in the number peripheral CD4 + T lymphocytes some HIV-infected patients (immune nonresponse to therapy). One crucial factors for immunodeficiency aggravation immune activation developing response bacterial products entry into bloodstream through damaged intestinal barrier. Additionally, ...

2017
Ran-hui Cha Shin Wook Kang Cheol Whee Park Dae Ryong Cha Ki Young Na Sung Gyun Kim Sun Ae Yoon Sejoong Kim Sang Youb Han Jung Hwan Park Jae Hyun Chang Chun Soo Lim Yon Su Kim

BACKGROUND We investigated the long-term effect of AST-120, which has been proposed as a therapeutic option against renal disease progression, in patients with advanced chronic kidney disease (CKD). METHODS We performed post-hoc analysis with a per-protocol group of the K-STAR study (Kremezin study against renal disease progression in Korea) that randomized participants into an AST-120 and a ...

2015
Kohei Aoki Yasushi Teshima Hidekazu Kondo Shotaro Saito Akira Fukui Naoya Fukunaga Tomoko Nawata Tatsuo Shimada Naohiko Takahashi Hirotaka Shibata

BACKGROUND Renal dysfunction is a major risk factor for atrial fibrillation (AF). The uremic toxin indoxyl sulfate may contribute to the progression of cardiac fibrosis and AF substrate in renal dysfunction. METHODS AND RESULTS Male Sprague-Dawley rats were assigned randomly to the following groups: 5/6 nephrectomy (5/6Nx) with vehicle, 5/6Nx with AST-120, sham procedure with vehicle, and sha...

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