BACKGROUND Patients with asthma may be more susceptible to adverse events (AEs) with sublingual immunotherapy tablet (SLIT-tablet) treatment, such as severe systemic reactions and asthma-related events. Using data from eight trials of grass SLIT-tablet in subjects with allergic rhinitis with/without conjunctivitis (AR/C), AE frequencies were determined in adults and children with and without re...

OBJECTIVE Allergic rhinitis can determine the presence and type of asthma. The main aim of this study was to evaluate the link between allergic rhinitis, asthma, and skin test sensitization in patients with allergic rhinitis. METHODS Patients with allergic rhinitis, aged 10 to 50 years, were consecutively enrolled at different allergy centers in Spain and Portugal. All the patients underwent ...

Asthma was the most common comorbidity in hospitalized patients during the 2009 influenza pandemic. For unknown reasons, hospitalized asthmatics had less severe outcomes and were less likely to die from pandemic influenza. Our data with primary human bronchial cells indicate that changes intrinsic to epithelial cells in asthma may protect against cytopathology induced by influenza virus. To fur...

The lung is constantly exposed to the environment and its microbial components. Infections of the respiratory tract are amongst the most common diseases. Several concepts describe how this microbial exposure interacts with allergic airway disease as it is found in patients with asthma. Infections are classical triggers of asthma exacerbations. In contrast, the hygiene hypothesis offers an expla...

BACKGROUND Many published epidemiologic studies confirm a marked increase in the prevalence of asthma and allergic rhinitis. The link between allergic rhinitis and asthma has been extensively studied and approximately 75% of patients with asthma have allergic rhinitis. The proportion of patients with asthma in populations of allergic rhinitis patients has not been well studied. OBJECTIVE The ...

Asthma affects a large number of patients in China, but comprehensive evaluation of risks associated with poor asthma control in asthmatic patients with nasal diseases was still limited. We conducted this study to provide a comprehensive estimate of asthma control in Chinese asthma patients with combined nasal diseases, to explore the effect of kinds of nasal diseases on the asthma control, and...

OBJECTIVES The aims of the study were to establish the prevalence of self-reported allergic rhinitis in an adult Nigerian population and to examine the relationship between asthma and allergic rhinitis. METHODS We conducted an epidemiological study of adults aged between 18 and 45 years in Ilorin, Nigeria from 2005 to 2006. An adaptation of the European Community Respiratory Health Survey que...

The last few decades have seen a rise in the prevalence of allergic diseases, including asthma and allergic rhinitis. The prevalence asthma is estimated to be around 300 million globally and around 35% in Europe and Australasia and 60 million people in the United States are affected by rhinitis. In India prevalence asthma is estimated to be around 2.38% and 20% to 26% people suffer from allergi...

BACKGROUND The prevalence of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis is increasing rapidly worldwide, especially among children and in western countries. This coincides with an increase in body mass index (BMI), which might be a major risk factor for atopic diseases. OBJECTIVES To study the relationship between high BMI and allergic diseases, as well as skin-...