Some information in this article is flawed, as the authors have not properly allowed for the latency period for cancer induction by radiation. A period of one year after the incident radiation may be insufficient. The latency period for induction of leukemia is 5–7 years, and for solid tumours is at least 10 years, so cancers occurring earlier than this should be considered to be naturally occu...

intensive induction therapy-in acute myeloid leukemia (aml), as in some other systemic malignancies- is a strategy fundamentally different from post-remission strategies. approaches like consolidation treatment, prolonged mainte nance, and autologous or allogeneic transplantation in the first remission are directed against minimal residual disease with a malignant cell population having survive...

Streptokinase (SK) is an extracellular protein comprising 414 amino acids with considerable clinical importance as a commonly used thrombolytic agent. Due to its wide spread application and clinical importance designing more efficient SK production platforms worth investigatinginvestigation. In this regard, a synthetic SK gene was optimized and cloned in to pET21b plasmid for periplasmic expres...

Background and Objective: The effect of opioids on the reproductive system has been studied as an attractive research field. In this study, the effect of morphine as an analgesic opioid was evaluated on the ovarian polycystic induction in the rat. Materials & Methods: In this study, 24 female virgin Wistar rats weighing 200-250 g were injected with morphine (1-10 mg/kg/day) for 9 days. Control ...

Bounded rationality questions backward induction, which however, does not exclude such reasoning when anticipation is easy. In our stochastic (alternating offer) bargaining experiment, there is a certain first-period pie and a known finite deadline. What is uncertain (except for the final period) is whether there is a further period. Whereas backward induction requires information about all lat...

Previous studies on the ring-opening polymerization of ε-caprolactone using structurally related aluminum complexes as pre-catalysts showed inconsistent trends in the total conversion time. We propose that an induction period for Al complexes for conversion to real catalytic species, Al alkoxide, should be considered because the total conversion time consists of both an induction period and pol...

We showed that brief exposures to amphotericin B (AmB) inhibited the induction of new Candida germ tubes and the lengthening of partially induced germ tubes. Blastoconidia with germ tubes were more susceptible to AmB killing, and this varied directly with the induction period and the AmB exposure period. AmB did not preferentially affect germ tube adherence to fibrin matrices.

A rapid induction system for synthesis of alpha-amylase by the funga Aspergillus oryzae M-13 was established. The mycelia were prepared from 20-h cultures grown on a peptone-glycerol medium and starved for 5 h; maltose was the optimum inducer tested. During h 1 of induction, formation of both intra- and extracellular alpha-amylases occurred at an almost identical rate (70 to 80 microgram/g of c...

purpose: the present study aimed to investigate the effect of immobilization stress on the induction of diabetes mellitus in rats. materials and methods: in this experimental study 30 mature male rats with an average weight of 200-220 gr were randomly divided into three groups of ten each. group i served as the control while the experiment groups were group ii (10 days) and groups iii (30 days)...

BACKGROUND To achieve multiple oocytes for in vitro fertilization, ovulation induction is induced by gonadotropins; however, it has several effects on oocytes and embryo quality and endometrium receptivity. The aim of this study was to assess ultrastructural changes of corpus luteum after ovarian induction using human menopausal gonadotropin (HMG) and human chorionic gonadotropin (HCG) during l...