objective: infantile spasms (is) is an age specific epileptic syndrome. due to poor response of is to conventional antiepileptic drugs, scientists are always on the lookout for newer, more effective drugs to treat the condition. materials & methods: in this study, 50 infants with is symptoms, aged between 2-24 months, were randomly divided into two equal groups, each treated either with vigabat...

Infantile hemangiomas are the most common infantile benign vascular tumor. While most infantile hemangiomas proliferate then involute, some may persist and require treatment for reasons including risk of disfigurement or functional impairment. Treatments currently include observation, pharmacological therapy, laser, cryosurgery, surgery and radiotherapy. Although pharmacological therapy is a we...

BACKGROUND A Danish population based matched case-control study of perinatal risk factors in children with infantile autism has provided some interesting and surprising observations regarding infantile autism and children born after assisted conception. METHODS AND RESULTS The cases (461) consisted of all children born between 1990 and 1999 and diagnosed with infantile autism in the Danish Ps...

Patients rarely consult physicians before developing coagulopathy or bleeding in most reported cases of superwarfarin intoxication. A 57-year-old woman ingested red-dyed pellets of anticoagulant rodenticide containing difethialone and warfarin as well as tablets of nitrazepam. Although she presented to the hospital in a comatose state, notable pink-colored excreta hinted at the consumption of a...

abstract: In this paper we describe the thin layer chromatographic separation of eight of the most frequently used benzodiazepine derivates (alprazolam, bromazepam, chlorazepate potassium, chlordiazepoxide, diazepam, nitrazepam, oxazepam) and their degradation products after acid hydrolysis. Our aim was not only to develop a simple, rapid and efficient method for their separation but also the o...

Ten subjects (mean age 57 years) took part in a crossover study between a food drink and nitrazepam 5 mg. They rated their anxiety and sleep quality. On half the sleep laboratory nights during baseline periods subjects were given an inert pill which they were told would improve sleep. A comparison was made between the six pill and six non-pill nights for each subject. Subjective ratings reveale...

BECAUSE one focus of Freud's work was his theory of infantile sexuality, there has been some interest in identifying other nineteenth-century writers who discussed this phenomenon.' Also, because of Freud's early papers on male hysteria, there has been interest in nineteenth-century beliefs about the occurrence of hysteria in males.2 Curiously enough, however, almost no one seems to have paid m...

A silver colloid technique to identify nucleolar organiser region associated protein (AgNOR) was applied to 16 fibrous proliferations of childhood and six low grade fibrosarcomas. The fibrous proliferations comprised five cases of infantile digital fibromatosis, seven of infantile desmoid type fibromatosis, and four of infantile myofibromatosis. The AgNORs were visualised as dots within the nuc...

Background: Benign idiopathic infantile masturbation (infantile dyskinesia) or also known as gratification disorder is a rare abnormal paroxysmal movement that occurs in children between 3 months and years old. This characterized by self-stimulation of the genitalia associated with unusual posturing movements. Therefore, it could mimic seizure.2 The diagnosis this may be perplexing scarcely rep...

Sir, Infantile haemangioma is a fairly common vascular tumour of the skin in infancy. In contrast, infantile subglottic haemangioma is rare, accounting for about 1.5% of all congenital laryngeal anomalies (1). However, it often causes stridor in infancy and sometimes leads to life-threatening respiratory distress (2). We report here a case of infantile haemangiomas on the face, neck and chest t...