periodontitis (pd) is known to be one of most prevalent worldwide chronic inflammatory diseases. there are several treatments including antibiotics for pd; however, since drug resistance is an increasing problem, new drugs particularly derived from plants with fewer side effects are required. the effects of trans-anethole on il-1 β and tnf-α level in a rat model of pd were investigated and comp...

background: heavy exercise cause muscle damage associated with production of inflammatory agents. the purpose of present study was to determine the effect of acute and 14-day coenzyme q10 supplementation on inflammatory, blood lactate and muscle damage in male middle-distance runners.   methods : eighteen male middle-distance runners in a randomized and quasi experimental study were allocated i...

the aim of this study was to test the therapeutic efficacy of sodium alginate in a rat model of trinitrobenzene sulfonic acid (tnbs)-induced inflammatory bowel disease. this experiment was carried out using 77 sprague-dawley rats which were divided into six groups; normal, control, prophylactic, therapeutic and two experimental groups. rats were sacrificed 1, 2, 3 and 6 weeks after colitis indu...

background: several studies have suggested that obesity-related inflammation can lead to altered iron metabolism as well as higher rates of iron deficiency in obese than in normal-weight subjects. given that at a population level, premenopausal women are at higher risk of iron deficiency, the purpose of this study was to investigate iron and inflammatory status in young overweight and obese wom...

objective(s): intestinal ischemia-reperfusion is a major problem, which may lead to multiorgan failure and death. the aim of this study was to evaluate the protective effects of dexmedetomidine on cell proliferation, antioxidant system, cell death, and structural integrity in intestinal injury induced by ischemia-reperfusion in rats. materials and methods: animals were randomized into three gro...

inflammatory myopathy is a paraneoplastic syndrome. inflammatory myopathy may be the first manifestation of underlying malignancy. it was reported in patients with colon cancer, breast cancer, ovarian cancer, lung cancer and non-hodgkin lymphoma. there are few reports regarding inflammatory myopathy in patients with gastric cancer. we want to present inflammatory myopathy as early manifestation...

background the incidence of inflammatory bowel disease (ibd) varies among different societies. the aim of this study is to determine the incidence rate of ibd in kerman, a city in southeast iran. methods all medical records that indicated a new diagnosis of ulcerative colitis (uc) or crohn`s disease (cd) were retrieved from the gastrointestinal endoscopy and pathology departments of 12 centers ...

context to provide an updated review of published literature on the anti-oxidant, anti-bacterial and anti-inflammatory properties of honey. evidence acquisition cinahl, biomed central, cochrane library, medline and embase data bases and reference lists were used to find randomized controlled trials and review articles. randomized controlled trials using honey with a comparator were reviewed, al...

conclusions end stage renal disease (esrd) have accelerated inflammatory conditions. simvastatin clearly lowers the serum levels of crp and il-6, and the white blood cell count in dialysis patients. administering simvastatin to dialysis patients is safe. results at baseline, each of treatment and control groups had similar characteristics. during the study, the average level of crp decreased in...

Background and objectives:Traditionally, Geum species from Rosaceae family have been used for treating inflammatory disorders. Geum iranicum Khatamsaz is endemic to Iran. The aim of this study was to investigate the antinociceptive and anti-inflammatory activities of Geum iranicum methanol extract G. iranicum methanol extract using classical ...