there are many effective chemothereutic agents used in influenza disease which some of them inhibit virus replication by interfering with fluv (influenza virus) viral binding or its penetration into cell membrane. a series of polyoxometalates compounds such as pom-523 and pm-504 have been synthesized and have showed inhibitory effects on viruses. in this study we examined anti influenza activit...

Influenza affects many lives worldwide each year during the months of October through February. The 2020-2021 influenza season saw a sharp decline in cases reported United States and other countries like Great Britain comparison to previous seasons. most likely explanations for this are safety measures taken COVID-19 pandemic, such as physical distancing, face mask use, better hand hygiene mass...

Influenza B is responsible for a significant proportion of the global morbidity, mortality and economic loss caused by influenza-related disease. Two antigenically distinct lineages co-circulate worldwide, often resulting in mismatches vaccine coverage when predictions fail. There are currently operational issues with gold standard serological assays influenza B, such as lack sensitivity requir...

background and aims: the novel approaches in influenza vaccination have targeted more conserved viral proteins such as nucleoprotein (np) to provide cross protection against all serotypes of influenza a viruses. influenza specific cytotoxic t lymphocytes (ctl) are able to lyse influenza-infected cells by recognition of np, the major target molecule in virus for ctl responses. on the other hand,...

background and aims: avian influenza (ai) h9n2 subtype was first reported to infect turkeys in the united states in 1966 and has been panzootic in europe and asia. the impact of avian influenza caused by h9n2 viruses in iran is now significantly more severe than in previous years. methods: sequence analysis and phylogenetic study of the complete coding region polymerase a (pa) gene of h9n2 subt...

high morbidity and mortality of influenza virus infection makes it an important disease world-wide. mouse is a very well-studied animal model for this disease with similar manifestation to human disease. it would be desirable to induce mucosal as well as circulating immune responses to obtain protection from infection and to decrease the spread of the virus. cell mediated immunity (proliferativ...

İnfluenza, sağlıklı çocuklarda genellikle kendi kendini sınırlayan bir enfeksiyon olarak karşımıza çıkmaktadır; ancak birçok çocuk hastada komplikasyonlar görülür. İnfluenza virüsleri, solunum sekresyonları ile temas (hapşırma, öksürme, konuşma, dokunma) veya kontamine nesneler yoluyla insandan insana bulaşır. Genellikle; hava, damlacık ve yolu Titreme yükselen ateş, baş ağrısı, miyalji, halsiz...

Influenza poses a significant threat to public health, particularly among the elderly, young children, and people with underlying dis-eases. The manifestation of severe conditions, such as pneumonia, highlights importance preventing spread influenza. An accurate cost-effective prediction host antigenic sub-types influenza A viruses is essential addressing this issue, in resource-constrained reg...