The spread of neurofibrillary tangle (NFT) pathology through the human brain is a hallmark of Alzheimer's disease (AD), which is thought to be caused by the propagation of "seeding" competent soluble misfolded tau. "TauC3", a C-terminally truncated form of tau that is generated by caspase-3 cleavage at D421, has previously been observed in NFTs and has been implicated in tau toxicity. Here we s...

The visualisation of 3D flow poses many challenges. Difficulties can stem from attempting to capture all flow features, the speed of computation, and spatial perception. Streamlines and stream surfaces are standard tools for visualising 3D flow. Although a variety of automatic seeding approaches have been proposed for streamlines, little work has been presented for stream surfaces. We present a...

22-151 ABSTRACT The main objective of this study was to evaluate the effectiveness and improved productivity of reduced tillage pasture renovation methods in the establishment of triple species pasture mixtures into an existing naturalized stand. Experimental treatments, 2 (low and high stocking rates) by 2 (frostand sod-seeding methods) factorial with an additional non-renovated pasture contro...

We study the power of a tournament organizer in manipulating the outcome of a balanced single-elimination tournament by fixing the initial seeding. This problem is known as agenda control for balanced voting trees. It is not known whether there is a polynomial time algorithm that computes a seeding for which a given player can win the tournament, even if the match outcomes for all pairwise play...

Numerical analysis of modal instability onset in fiber amplifiers Report Title Numerical analysis of the onset of modal instability in fiber amplifiers is presented. Specifically calculations of the evolution of the intensity fluctuation spectrum along the fiber for a sampling point offset from the core center are presented for different instability onset conditions. These include seeding with ...

Extracranial and meningeal seeding of glioblastoma multiforme is rare. We report herein a case of glioblastoma in a 41-year-old man who underwent surgical resection, concomitant chemoradiotherapy (CCRT) and seven courses of adjuvant chemotherapy with temozolomide. The patient then complained of intermittent severe lower back pain and gait disturbance. Imaging studies demonstrated that although ...

A critical element of word of mouth (WOM) marketing (aka buzz marketing) is to identify central actors with high degree in the social network to serve as seeds. However, seed identification typically requires data on the full network structure, which is often unavailable. We examine WOM seeding strategies motivated by the friendship paradox to get higher degree nodes without knowing network str...

Tauopathies such as Alzheimer's disease (AD) feature progressive intraneuronal deposition of aggregated tau protein. The cause is unknown, but in experimental systems trans-cellular propagation of tau pathology resembles prion pathogenesis. Tau aggregate inoculation into mice produces transmissible pathology, and tau forms distinct strains, i.e. conformers that faithfully replicate and create p...

The purpose ofthis randomized prospective study was to assess the efficacy of local radiotherapy in prevent¬ ing malignant seeding along invasive diagnostic pro¬ cedures (cytology, needle biopsy, thoracoscopy, or chest tube placement) in patients with malignant pleural mesothelioma. Forty consecutive patients with histologically proven malignant mesothelioma were enrolled. Twenty patients recei...

With the climbing costs of cotton production, producers must ensure optimal returns on their cotton crops in order to make a profit. The groundwork for a high yielding crop has to start with an accurate and efficient planting system to ensure an optimal stand. However, there are a variety of new systems and techniques to incorporate compared to the conventional system that has been used for so ...